Mephobarbital

Known as: Metilfenobarbitale, Metilfenobarbital, 5-Ethyl-1-methyl-5-phenylbarbituric acid 
A barbiturate that is metabolized to PHENOBARBITAL. It has been used for similar purposes, especially in EPILEPSY, but there is no evidence… (More)
National Institutes of Health

Papers overview

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2004
2004
We sequenced all nine exons and exon-intron junctions of the cytochrome P450 2C19 (CYP2C19) gene from a Japanese subject with a… (More)
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Highly Cited
2001
Highly Cited
2001
Purpose. A new mucus-secreting in vitro drug absorption model based on monolayers of goblet-cell like sub-clones of the human… (More)
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Highly Cited
2000
Highly Cited
2000
PURPOSE The study goal was to assess teratogenic effects of antiepileptic drugs (AEDs) through the use of a surveillance system… (More)
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2000
2000
Pyrethroids act on mammalian sodium channels, but we have previously shown that low concentrations of the type II pyrethroid… (More)
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1995
1995
The effects of the CYP2C19 substrates, mephenytoin, methsuximide and mephobarbitone on the metabolism of proguanil and… (More)
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1991
1991
Steady-state plasma antiepileptic drug (AED) concentrations were measured at intervals throughout pregnancy and during the… (More)
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1990
1990
In this clinical investigation, four groups of subjects (eight young women and eight young men [age range, 18 to 25 years], and… (More)
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1986
1986
Some pediatric neurologists maintain that mephobarbital (Mebaral) causes fewer behavioral side effects than phenobarbital… (More)
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1986
1986
The simultaneous dosing of two drugs with co-regulated genetic polymorphisms determined by a single cytochrome P-450 isozyme… (More)
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1985
1985
The 8-hour urinary recovery of 4-hydroxy-mephobarbital has been measured after oral administration of racemic mephobarbital (90… (More)
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