Skip to search formSkip to main contentSkip to account menu

Melphalan

Known as: 4-[bis(2-chloroethyl)amino]-L-phenylalanine, 3-P-(Di(2-chloroethyl)amino)-phenyl-L-alanine, 4-(Bis(2-chloroethyl)amino)phenylalanine 
A phenylalanine derivative of nitrogen mustard with antineoplastic activity. Melphalan alkylates DNA at the N7 position of guanine and induces DNA… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2021
Highly Cited
2021
  • R. Baggott
  • Social Policy & Administration
  • 2021
  • Corpus ID: 222064452
Background: Little is known about patients who frequently visit the emergency department (ED) for acute exacerbation of chronic… 
Highly Cited
2018
Highly Cited
2018
BACKGROUND The combination of bortezomib, melphalan, and prednisone is a standard treatment for patients with newly diagnosed… 
Highly Cited
2010
Highly Cited
2010
PURPOSE The combination of bortezomib-melphalan-prednisone (VMP) is a new standard of care for newly diagnosed multiple myeloma… 
Highly Cited
2008
Highly Cited
2008
BACKGROUND The standard treatment for patients with multiple myeloma who are not candidates for high-dose therapy is melphalan… 
Review
2004
Review
2004
Context AL amyloidosis responds poorly to oral chemotherapy and rarely leads to elimination of plasma cell dyscrasia. Amyloid… 
Highly Cited
2001
Highly Cited
2001
A reduced-intensity preparative regimen consisting of melphalan and a purine analog was evaluated for allogeneic transplantation… 
Highly Cited
1997
Highly Cited
1997
BACKGROUND Primary systemic amyloidosis is an uncommon disease characterized by the accumulation in vital organs of a fibrillar… 
Highly Cited
1992
Highly Cited
1992
PURPOSE To determine the toxicity and the therapeutic efficacy of the combination of the recombinant tumor necrosis factor alpha… 
Highly Cited
1980
Highly Cited
1980