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The standard treatment for patients with multiple myeloma who are not candidates for high-dose therapy is melphalan… Expand BACKGROUND
In multiple myeloma, combination chemotherapy with melphalan plus prednisone is still regarded as the standard of care… Expand BACKGROUND
Since 1960, oral melphalan and prednisone (MP) has been regarded as the standard of care in elderly multiple myeloma… Expand Context AL amyloidosis responds poorly to oral chemotherapy and rarely leads to elimination of plasma cell dyscrasia. Amyloid… Expand A reduced-intensity preparative regimen consisting of melphalan and a purine analog was evaluated for allogeneic transplantation… Expand BACKGROUND
Primary systemic amyloidosis is an uncommon disease characterized by the accumulation in vital organs of a fibrillar… Expand PURPOSE
To determine the toxicity and the therapeutic efficacy of the combination of the recombinant tumor necrosis factor alpha… Expand 1 previously untreated patient with plasma-cell leukaemia and 8 patients with myeloma (4 previously untreated) were treated with… Expand Of 183 patients with multiple myeloma treated with melphalan, 43% demonstrated an objective response. Of the evaluable cases, 70… Expand