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Melanoma-Associated Antigen B2

Known as: MAGE-B2 Antigen, MAGE XP-2 Antigen, Cancer/Testis Antigen 3.2 
Melanoma-associated antigen B2 (319 aa, ~35 kDa) is encoded by the human MAGEB2 gene. This protein is involved in enhancing ubiquitin ligase activity… Expand
National Institutes of Health

Related topics

Related topics

4 relations
Cancer Promoting GenesMAGEB2 geneMetastasis InductionNeoplastic Cell Transformation

Papers overview

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Highly Cited
2017
Highly Cited
2017
IgG antibodies to dengue enhanced for FcγRIIIA binding determine disease severity
A rare ability to enhance dengue virus disease In some cases, secondary infections of dengue virus can be extremely serious and… Expand
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Highly Cited
2016
Highly Cited
2016
Efficacy of the MAGE-A3 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small-cell lung cancer (MAGRIT): a randomised, double-blind, placebo-controlled…
BACKGROUND Fewer than half of the patients with completely resected non-small-cell lung cancer (NSCLC) are cured. Since the… Expand
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Highly Cited
2011
Highly Cited
2011
SwissDock, a protein-small molecule docking web service based on EADock DSS
Most life science processes involve, at the atomic scale, recognition between two molecules. The prediction of such interactions… Expand
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Highly Cited
2011
Highly Cited
2011
Fast docking using the CHARMM force field with EADock DSS
The prediction of binding modes (BMs) occurring between a small molecule and a target protein of biological interest has become… Expand
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Highly Cited
2010
Highly Cited
2010
Targeting of DEC-205 on human dendritic cells results in efficient MHC class II-restricted antigen presentation.
The use of dendritic cells (DCs) in therapeutic cancer vaccination requires their loading with tumor-specific antigen(s). DEC-205… Expand
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Highly Cited
2007
Highly Cited
2007
Cancer/Testis Genes in Multiple Myeloma: Expression Patterns and Prognosis Value Determined by Microarray Analysis1
Cancer-testis (CT) Ags are expressed in testis and malignant tumors but rarely in nongametogenic tissues. Due to this pattern… Expand
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Highly Cited
2005
Highly Cited
2005
MAGE-A1-, MAGE-A10-, and gp100-Derived Peptides Are Immunogenic When Combined with Granulocyte-Macrophage Colony-Stimulating Factor and Montanide ISA-51 Adjuvant and Administered as Part of a…
Twelve peptides derived from melanocyte differentiation proteins and cancer-testis Ags were combined and administered in a single… Expand
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Highly Cited
2004
Highly Cited
2004
Application of Information Technology: Translating Research into Practice: Organizational Issues in Implementing Automated Decision Support for Hypertension in Three Medical Centers
Information technology can support the implementation of clinical research findings in practice settings. Technology can address… Expand
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Highly Cited
2002
Highly Cited
2002
Design and implementation of microarray gene expression markup language (MAGE-ML)
BackgroundMeaningful exchange of microarray data is currently difficult because it is rare that published data provide sufficient… Expand
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Highly Cited
2001
Highly Cited
2001
Heterogeneous T-cell response to MAGE-A10(254-262): high avidity-specific cytolytic T lymphocytes show superior antitumor activity.
MAGE-encoded antigens, which are expressed by tumors of many histological types but not in normal tissues, are suitable… Expand
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