Melanocortins

Known as: Melanocortins [Chemical/Ingredient] 
Peptides derived from pro-opiomelanocortin (POMC) which can stimulate MELANOCYTES or CORTICOTROPHS. Melanocortins include ACTH; ALPHA-MSH; and other… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Melanocortin-4 receptor (MC4R) mutations cause dysregulation of energy balance and hyperinsulinemia. We have used mouse models to… (More)
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Review
2010
Review
2010
Excess weight gain contributes to increased blood pressure in most patients with essential hypertension. Although the mechanisms… (More)
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Highly Cited
2003
Highly Cited
2003
The melanocortin-4 receptor (MC4-R) is an important regulator of energy homeostasis, and evidence suggests that MC4-R-expressing… (More)
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Highly Cited
2002
Highly Cited
2002
Like leptin, the pancreatic hormone insulin is an important adiposity signal to the brain. We report that the hypothalamic… (More)
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Highly Cited
2001
Highly Cited
2001
  • Ira GantzSO, Hiroto Miwall, +5 authors Tadataka Yamadal
  • 2001
The recent cloning of three melanocortin receptors suggests an unexpected diversity in this family of seven transmembrane G… (More)
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Highly Cited
2001
Highly Cited
2001
The administration of leptin to leptin-deficient humans, and the analogous Lepob/Lepob mice, effectively reduces hyperphagia and… (More)
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Highly Cited
2000
Highly Cited
2000
Prolonged fasting is associated with a downregulation of the hypothalamo-pituitary thyroid (H-P-T) axis, which is reversed by… (More)
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Highly Cited
1999
Highly Cited
1999
Pro-opiomelanocortin (POMC)-derived peptides (the melanocortins adrenocorticotropin, α-, β- and γ-melanocyte stimulating hormone… (More)
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Highly Cited
1999
Highly Cited
1999
Energy stores are held relatively constant in many mammals. The circuitry necessary for maintaining energy homeostasis should (1… (More)
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Highly Cited
1998
Highly Cited
1998
Neuropeptide Y (NPY) stimulates food intake and promotes weight gain, whereas melanocortins have the opposite effect. Yet both… (More)
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