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Diagnostic accuracy of the vegetative and minimally conscious state: Clinical consensus versus standardized neurobehavioral assessment
BackgroundPreviously published studies have reported that up to 43% of patients with disorders of consciousness are erroneously assigned a diagnosis of vegetative state (VS). However, no recentExpand
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Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin
The generation of cortical projection neurons relies on the coordination of radial migration with branching. Here, we report that the multisubunit histone acetyltransferase Elongator complex, whichExpand
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Baseline brain activity fluctuations predict somatosensory perception in humans
In perceptual experiments, within-individual fluctuations in perception are observed across multiple presentations of the same stimuli, a phenomenon that remains only partially understood. Here, byExpand
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From unresponsive wakefulness to minimally conscious PLUS and functional locked-in syndromes: recent advances in our understanding of disorders of consciousness
Functional neuroimaging and electrophysiology studies are changing our understanding of patients with coma and related states. Some severely brain damaged patients may show residual corticalExpand
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Default network connectivity reflects the level of consciousness in non-communicative brain-damaged patients.
The 'default network' is defined as a set of areas, encompassing posterior-cingulate/precuneus, anterior cingulate/mesiofrontal cortex and temporo-parietal junctions, that show more activity at restExpand
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Two Distinct Neuronal Networks Mediate the Awareness of Environment and of Self
TLDR
Evidence from functional neuroimaging studies on resting state suggests that there are two distinct anticorrelated cortical systems that mediate conscious awareness: an “extrinsic” system that encompasses lateral fronto-parietal areas and has been linked with processes of external input (external awareness), and a “default network” that encompasses mainly medial brain areas and is associated with internal processes. Expand
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When thoughts become action: An fMRI paradigm to study volitional brain activity in non-communicative brain injured patients
TLDR
The assessment of voluntary behavior in non-communicative brain injured patients is often challenging due to the existence of profound motor impairment. Expand
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Plasticity of Cultured Mesenchymal Stem Cells: Switch from Nestin‐Positive to Excitable Neuron‐Like Phenotype
Bone marrow mesenchymal stem cells (MSCs) can differentiate into several types of mesenchymal cells, including osteocytes, chondrocytes, and adipocytes, but, under appropriate experimentalExpand
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Autocrine/Paracrine Activation of the GABAA Receptor Inhibits the Proliferation of Neurogenic Polysialylated Neural Cell Adhesion Molecule-Positive (PSA-NCAM+) Precursor Cells from Postnatal Striatum
GABA and its type A receptor (GABAAR) are present in the immature CNS and may function as growth-regulatory signals during the development of embryonic neural precursor cells. In the present study,Expand
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Auditory processing in severely brain injured patients: differences between the minimally conscious state and the persistent vegetative state.
BACKGROUND The minimally conscious state (MCS) is a recently defined clinical condition; it differs from the persistent vegetative state (PVS) by the presence of inconsistent, but clearlyExpand
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