Megakaryocytes

Known as: Megakaryocytic, Megalokaryocyte, Megakaryocyte 
Very large bone marrow cells which release mature blood platelets.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
In the bone marrow, hematopoietic stem cells (HSCs) lodge in specialized microenvironments that tightly control the proliferative… (More)
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Highly Cited
2008
Highly Cited
2008
Lineage specification is a critical issue in developmental and regenerative biology. We hypothesized that microRNAs (miRNAs) are… (More)
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Highly Cited
2003
Highly Cited
2003
Chronic immune thrombocytopenic purpura (ITP) is manifested by autoantibody-induced platelet destruction. Platelet turnover… (More)
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Highly Cited
1999
Highly Cited
1999
In the absence of the hematopoietic transcription factor GATA-1, mice develop thrombocytopenia and an increased number of… (More)
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Highly Cited
1999
Highly Cited
1999
Megakaryocytes release mature platelets in a complex process. Platelets are known to be released from intermediate structures… (More)
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Highly Cited
1997
Highly Cited
1997
Transcription factor GATA-1 is essential for red blood cell maturation and, therefore, for survival of developing mouse embryos… (More)
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Highly Cited
1997
Highly Cited
1997
Thrombopoietin (TPO) is a recently cloned cytokine that binds to its receptor, Mpl, and promotes hematopoietic expansion and… (More)
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Highly Cited
1995
Highly Cited
1995
Despite the importance of blood platelets in health and disease, the mechanisms regulating their formation within megakaryocytes… (More)
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Highly Cited
1994
Highly Cited
1994
THE development of blood cells including expansion of megakaryocyte progenitor cells requires the interplay of marrow stromal… (More)
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Highly Cited
1994
Highly Cited
1994
A novel megakaryocyte growth and development factor (MGDF) has been identified in aplastic canine plasma, and its cDNAs have been… (More)
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