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Matrix Metalloproteinase 17

Known as: Membrane Type 4 Matrix Metalloproteinase, Metalloproteinase 17, Matrix, Metalloproteinase, MMP17 
A membrane-type metalloproteinase that is associated with the CELL MEMBRANE via a GLYCOSYL-PHOSPHATIDYLINOSITOL linkage. It is synthesized as an… Expand
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
The passage of leukocytes through basement membranes involves proteolytic degradation of extracellular matrix (ECM) components… Expand
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Highly Cited
2001
Highly Cited
2001
Migratory cells including invasive tumor cells frequently express CD44, a major receptor for hyaluronan and membrane-type 1… Expand
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Highly Cited
2001
Highly Cited
2001
Cell invasion requires cooperation between adhesion receptors and matrix metalloproteinases (MMPs). Membrane type (MT)-MMPs have… Expand
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Highly Cited
2000
Highly Cited
2000
Membrane type 4 matrix metalloproteinase (MT4-MMP) shows the least sequence homology to the other MT-MMPs, suggesting a distinct… Expand
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Highly Cited
2000
Highly Cited
2000
In the present study, we used in situ hybridization to study 36 primary hepatocellular carcinomas (HCCs) and 35 pancreatic… Expand
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Highly Cited
2000
Highly Cited
2000
Matrix metalloproteinase (MMP)-9 is an endopeptidase that digests basement membrane type IV collagen. Enhanced expression has… Expand
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Highly Cited
1999
Highly Cited
1999
Among the five membrane-type matrix metalloproteinases (MT-MMPs), MT1-, MT2-, MT3-, and MT5-MMPs have about a 20-amino acid… Expand
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Highly Cited
1997
Highly Cited
1997
Activation of the zymogen of matrix metalloproteinase 2 (proMMP-2, progelatinase A) possibly is one of the key steps in invasion… Expand
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Highly Cited
1997
Highly Cited
1997
We have previously demonstrated that fibroblasts and invasive human breast carcinoma (HBC) cells specifically activate matrix… Expand
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Highly Cited
1996
Highly Cited
1996
Overexpression of membrane-type matrix metalloproteinase (MT-MMP-1) results in the activation of both endogenous and exogenous 72… Expand
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