Mast cell degranulation

Known as: Degranulation, Mast Cell Granule Exocytosis 
The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell… (More)
National Institutes of Health

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Cellular MembraneFAMILIAL COLD AUTOINFLAMMATORY SYNDROME 3mast cell granuleregulation of mast cell degranulation

Papers overview

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Review
2017
Review
2017
Neutrophil Extracellular Traps and Its Implications in Inflammation: An Overview
In addition to physical barriers, neutrophils are considered a part of the first line of immune defense. They can be found in the… (More)
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Review
2012
Review
2012
Mast cells and inflammation.
Mast cells are well known for their role in allergic and anaphylactic reactions, as well as their involvement in acquired and… (More)
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Highly Cited
2011
Highly Cited
2011
Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis.
IL-17 and IL-23 are known to be absolutely central to psoriasis pathogenesis because drugs targeting either cytokine are highly… (More)
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Highly Cited
2008
Highly Cited
2008
CD4+CD25+ regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction.
T regulatory (Treg) cells play a role in the suppression of immune responses, thus serving to induce tolerance and control… (More)
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Review
2008
Review
2008
Mast cells and mastocytosis.
Mast cells have been recognized for well over 100 years. With time, human mast cells have been documented to originate from CD34… (More)
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Highly Cited
2007
Highly Cited
2007
Mast cell degranulation activates a pain pathway underlying migraine headache
Intracranial headaches such as that of migraine are generally accepted to be mediated by prolonged activation of meningeal… (More)
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Highly Cited
2002
Highly Cited
2002
Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation
FcεRI activation of mast cells is thought to involve Lyn and Syk kinases proximal to the receptor and the signaling complex… (More)
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Highly Cited
1998
Highly Cited
1998
The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation.
To clarify the role that the src homology 2-containing inositol phosphatase (SHIP) plays in mast cell degranulation, the gene for… (More)
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Highly Cited
1998
Highly Cited
1998
Corticotropin-releasing hormone induces skin mast cell degranulation and increased vascular permeability, a possible explanation for its proinflammatory effects.
Mast cells are involved in atopic disorders, often exacerbated by stress, and are located perivascularly close to sympathetic and… (More)
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Highly Cited
1997
Highly Cited
1997
Accumulation of major histocompatibility complex class II molecules in mast cell secretory granules and their release upon degranulation.
To investigate the relationship between major histocompatibility complex (MHC) class II compartments, secretory granules, and… (More)
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