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Mast cell degranulation

Known as: Degranulation, Mast Cell Granule Exocytosis 
The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell… Expand
National Institutes of Health

Related topics

Related topics

4 relations
Cellular MembraneFAMILIAL COLD AUTOINFLAMMATORY SYNDROME 3mast cell granuleregulation of mast cell degranulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Purine Release, Metabolism, and Signaling in the Inflammatory Response.
ATP, NAD+, and nucleic acids are abundant purines that, in addition to having critical intracellular functions, have evolved… Expand
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Review
2018
Review
2018
Mast cells as protectors of health.
Mast cells (MCs), which are well known for their effector functions in TH2-skewed allergic and also autoimmune inflammation, have… Expand
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Review
2018
Review
2018
Formyl-Peptide Receptors in Infection, Inflammation, and Cancer.
Formyl-peptide receptors (FPRs) recognize bacterial and mitochondrial formylated peptides as well as endogenous non-formylated… Expand
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Review
2016
Review
2016
Mast Cell: A Multi-Functional Master Cell
Mast cells are immune cells of the myeloid lineage and are present in connective tissues throughout the body. The activation and… Expand
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Highly Cited
2011
Highly Cited
2011
Mast Cells and Neutrophils Release IL-17 through Extracellular Trap Formation in Psoriasis
IL-17 and IL-23 are known to be absolutely central to psoriasis pathogenesis because drugs targeting either cytokine are highly… Expand
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Highly Cited
2010
Highly Cited
2010
Circulating Mitochondrial DAMPs Cause Inflammatory Responses to Injury
Injury causes a systemic inflammatory response syndrome (SIRS) that is clinically much like sepsis. Microbial pathogen-associated… Expand
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Highly Cited
2006
Highly Cited
2006
HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells.
Establishing a CD8(+) T cell-mediated immune correlate of protection in HIV disease is crucial to the development of vaccines… Expand
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Highly Cited
2003
Highly Cited
2003
Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation.
Flow cytometric detection of antigen-specific CD8+ T cells has previously been limited to MHC-class I tetramer staining or… Expand
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Highly Cited
2002
Highly Cited
2002
Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation
FcεRI activation of mast cells is thought to involve Lyn and Syk kinases proximal to the receptor and the signaling complex… Expand
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Highly Cited
1991
Highly Cited
1991
Human dermal mast cells contain and release tumor necrosis factor alpha, which induces endothelial leukocyte adhesion molecule 1.
Tumor necrosis factor alpha (TNF-alpha) is a proinflammatory cytokine that mediates endothelial leukocyte interactions by… Expand
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