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Malonate
Â
Topic mentions per year
Topic mentions per year
1943-2018
0
50
100
150
1943
2017
Related topics
Related topics
6 relations
Maleate
Broader (4)
Maleates
Malonates
dicarboxylate
malonic acid
Narrower (1)
methylmalonate
Related mentions per year
Related mentions per year
1936-2018
1940
1960
1980
2000
2020
Malonate
dicarboxylate
malonic acid
Maleate
methylmalonate
Malonates
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease.
Onintza Sagredo
,
Sara González
,
+9 authors
Javier Fernández-Ruiz
Glia
2009
Cannabinoid agonists might serve as neuroprotective agents in neurodegenerative disorders. Here, we examined this hypothesis in a…Â
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Highly Cited
2000
Highly Cited
2000
Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.
Peter Klivenyi
,
Ole A. Andreassen
,
+7 authors
M Flynt Beal
The Journal of neuroscience : the official…
2000
Glutathione peroxidase (GSHPx) is a critical intracellular enzyme involved in detoxification of hydrogen peroxide (H(2)O(2)) to…Â
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Highly Cited
2000
Highly Cited
2000
Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo.
N. Malik
,
Ruedeekorn Wiwattanapatapee
,
+6 authors
R. Duncan
Journal of controlled release : official journal…
2000
Dendrimers are highly branched macromolecules of low polydispersity that provide many exciting opportunities for design of novel…Â
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Highly Cited
1998
Highly Cited
1998
Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease.
Roger Matthews
,
L. Yang
,
+4 authors
M Flynt Beal
The Journal of neuroscience : the official…
1998
The gene defect in Huntington's disease (HD) may result in an impairment of energy metabolism. Malonate and 3-nitropropionic acid…Â
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Highly Cited
1997
Highly Cited
1997
High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria.
Sergei S Korshunov
,
Vladimir P. Skulachev
,
Alexander Starkov
FEBS letters
1997
Formation of H2O2 has been studied in rat heart mitochondria, pretreated with H2O2 and aminotriazole to lower their antioxidant…Â
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Highly Cited
1996
Highly Cited
1996
Mitochondrial defect in Huntington's disease caudate nucleus.
Min Gu
,
M T Gash
,
V. Mann
,
F. Javoy-Agid
,
J. M. Cooper
,
Antony H Schapira
Annals of neurology
1996
Although the Huntington's disease (HD) gene defect has been identified, the structure and function of the abnormal gene product…Â
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1994
1994
Malonate produces striatal lesions by indirect NMDA receptor activation.
Robert Mikael Henshaw
,
Brian Jenkins
,
+4 authors
M Flynt Beal
Brain research
1994
We previously showed that local striatal injections of malonate produce age-dependent excitotoxic lesions. In the present study…Â
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1994
1994
Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate.
M Flynt Beal
,
Don Henshaw
,
Brian Jenkins
,
Benjamin Rosen
,
Jan Schulz
Annals of neurology
1994
A potential mechanism of neuronal injury in neurodegenerative diseases is a defect in energy metabolism that may lead to slow…Â
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Highly Cited
1993
Highly Cited
1993
Age-dependent striatal excitotoxic lesions produced by the endogenous mitochondrial inhibitor malonate.
M Flynt Beal
,
E Brouillet
,
B Stephen Jenkins
,
Robert Mikael Henshaw
,
Brittany L Rosen
,
B. T. Hyman
Journal of neurochemistry
1993
Intrastriatal injection of malonate, a reversible inhibitor of succinate dehydrogenase (SDH), produced age-dependent striatal…Â
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Highly Cited
1992
Highly Cited
1992
Manganese(II) oxidation by manganese peroxidase from the basidiomycete Phanerochaete chrysosporium. Kinetic mechanism and role of chelators.
Hiroyuki Wariishi
,
K. Punitha Valli
,
Michael H Gold
The Journal of biological chemistry
1992
Manganese oxidation by manganese peroxidase (MnP) was investigated. Stoichiometric, kinetic, and MnII binding studies…Â
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