MYH11 gene

Known as: SMHC, SMMHC, SMOOTH MUSCLE MYOSIN HEAVY CHAIN 
This gene plays a regulatory role in muscle contraction and the required ATP hydrolysis.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Thoracic aortic aneurysm/dissection (TAAD) is a common phenotype that may occur as an isolated manifestation or within… (More)
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2012
2012
RATIONALE Mutations in myosin heavy chain (MYH11) cause autosomal dominant inheritance of thoracic aortic aneurysms and… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE We previously demonstrated that upregulation of intermediate-conductance Ca(2+)-activated K(+) channels (K(Ca)3.1) is… (More)
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2008
2008
Tissue-specific knockouts generated through Cre-loxP recombination have become an important tool to manipulate the mouse genome… (More)
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2006
2006
A hallmark of smooth muscle cell (SMC) phenotypic modulation in atherosclerosis and restenosis is suppression of SMC… (More)
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Highly Cited
2004
Highly Cited
2004
Knockout of transforming growth factor (TGF)-beta1 or components of its signaling pathway leads to embryonic death in mice due to… (More)
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Highly Cited
2004
Highly Cited
2004
Vascular smooth muscle cell (SMC) contraction is mediated in part by calcium influx through L-type voltage-gated Ca2+ channels… (More)
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2000
2000
The use of genetically modified mice has been an important model system to study gene function in cardiovascular development and… (More)
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Highly Cited
1996
Highly Cited
1996
The fusion oncogene CBFB-MYH11 is generated by a chromosome 16 inversion in human acute myeloid leukemia subtype M4Eo. Mouse… (More)
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Highly Cited
1993
Highly Cited
1993
The pericentric inversion of chromosome 16 [inv(16)(p13q22)] is a characteristic karyotypic abnormality associated with acute… (More)
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