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MTR gene

Known as: 5-methyltetrahydrofolate-homocysteine methyltransferase, MTR, TETRAHYDROPTEROYLGLUTAMATE METHYLTRANSFERASE 
This gene plays a role in methionine biosynthesis.
National Institutes of Health

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Related topics

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Amino Acid BiosynthesisMTR protein, humanMalesMethylation

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MTR wt Allele

Papers overview

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2019
2019
Association of MTHFR 677C>T, 1298A>C and MTR 2756A>G Polymorphisms with Risk of Retinoblastoma.
BACKGROUND The MTHFR 677C>T, 1298A>C and MTR 2756A>G polymorphisms have been investigated in several different cancer types… 
2014
2014
Gene-Environment Interactions and the Risk of Childhood Acute Lymphoblastic Leukemia: Exploring the Role of Maternal Folate Genes and Folic Acid Fortification
Few studies have evaluated the interaction of folic acid fortification and folate metabolic genes on the risk of childhood acute… 
2013
2013
Interaction between methionine synthase isoforms and MMACHC: characterization in cblG-variant, cblG and cblC inherited causes of megaloblastic anaemia.
The cblG and cblC disorders of cobalamin (Cbl) metabolism are two inherited causes of megaloblastic anaemia. In cblG, mutations… 
2011
2011
Association of MTHFR, MTR, and MTRR polymorphisms with Parkinson's disease among ethnic Chinese in Taiwan.
2007
2007
The MTR A2756G polymorphism is associated with an increase of plasma homocysteine concentration in Brazilian individuals with Down syndrome.
Individuals with Down syndrome (DS) present decreased homocysteine (Hcy) concentration, reflecting a functional folate deficiency… 
2005
2005
Disturbed visual system function in methionine synthase deficiency
BackgroundIsolated functional methionine synthase deficiency occurs in the cblE and cblG defects of methylcobalamin metabolism… 
2005
2005
A methionine synthase homolog is associated with secretory vesicles in tobacco pollen tubes
Seven isoforms of 85 kDa polypeptides (p85) were identified as methionine synthase (MetE) homologs by partial aminoacid… 
1989
1989
Selective deficiencies of methyl-B12 (cblE and cblG)
1986
1986
Perturbation of methionine metabolism in sheep with nitrous-oxide-induced inactivation of cobalamin.
Exposure of sheep to 36% nitrous oxide for 8 days (2-hr per day) led to 90%, 82% and 74% inhibition of 5-methyltetrahydrofolate… 
1985
1985
Regulation of methyl group metabolism in lactating ewes.
The effect of lactation on a number of enzymes involved in transmethylation reactions and the secretion of major methyl compounds… 
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