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MTHFD2 gene

Known as: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase, Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase Gene, METHYLENETETRAHYDROFOLATE DEHYDROGENASE 2 
This gene is involved in the metabolism of folic acid.
National Institutes of Health

Papers overview

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2018
2018
Abstract Background Overcoming oxidative stress is a critical step for tumor progression; however, the underlying mechanisms in… Expand
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2017
2017
Aberrant expression of microRNA-92a (miR-92a) has been investigated in various cancers. However, the function and mechanism of… Expand
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Highly Cited
2016
Highly Cited
2016
Controlling supplies for DNA and RNA synthesis The mTORC1 protein kinase complex regulates anabolic metabolism and coordinates… Expand
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2016
2016
Pikman et al. demonstrate that the mitochondrial enzyme MTHFD2 is a potential therapeutic target in acute myeloid leukemia. 
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2016
2016
Methylenetetrahydrofolate dehydrogenase (NAD(P)+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (MTHFD2) is a… Expand
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2015
2015
Folate metabolism is central to cell proliferation and a target of commonly used cancer chemotherapeutics. In particular, the… Expand
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Highly Cited
2014
Highly Cited
2014
Metabolic remodeling is now widely regarded as a hallmark of cancer, but it is not clear whether individual metabolic strategies… Expand
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2014
2014
The aim of this study was to investigate the expression levels of methylenetetrahydrofolate dehydrogenase (NADP + -dependent) 2… Expand
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Highly Cited
2013
Highly Cited
2013
Vimentin is an intermediate filament protein, with a key role in the epithelial to mesenchymal transition as well as cell… Expand
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Highly Cited
2012
Highly Cited
2012
Background: Dysregulation of miRNAs is associated with breast cancer. Results: MiR-9 overexpression and transcriptome analysis… Expand
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