MTHFD2 gene

Known as: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase, Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase Gene, METHYLENETETRAHYDROFOLATE DEHYDROGENASE 2 
This gene is involved in the metabolism of folic acid.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2018
024620102018

Papers overview

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Highly Cited
2016
Highly Cited
2016
In response to growth signals, mechanistic target of rapamycin complex 1 (mTORC1) stimulates anabolic processes underlying cell… (More)
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2016
2016
Drugs targeting metabolism have formed the backbone of therapy for some cancers. We sought to identify new such targets in acute… (More)
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2016
2016
Methylenetetrahydrofolate dehydrogenase (NAD(P)+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (MTHFD2) is a… (More)
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2015
2015
Rapidly proliferating tumors attempt to meet the demands for nucleotide biosynthesis by upregulating folate pathways that provide… (More)
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Highly Cited
2014
Highly Cited
2014
Metabolic remodeling is now widely regarded as a hallmark of cancer, but it is not clear whether individual metabolic strategies… (More)
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2014
2014
The aim of this study was to investigate the expression levels of methylenetetrahydrofolate dehydrogenase (NADP + -dependent) 2… (More)
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2014
2014
KRAS gene mutation is linked to poor prognosis and resistance to therapeutics in non-small cell lung cancer (NSCLC). In this… (More)
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2013
2013
Vimentin is an intermediate filament protein, with a key role in the epithelial to mesenchymal transition as well as cell… (More)
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Highly Cited
2012
Highly Cited
2012
Although underexpression of miR-9 in cancer cells is reported in many cancer types, it is currently difficult to classify miR-9… (More)
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2010
2010
Mitochondrial folate-dependent one-carbon (1-C) metabolism converts 1-C donors such as serine and glycine to formate, which is… (More)
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