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MTDH wt Allele

Known as: AEG1, AEG-1, Metadherin wt Allele 
Human MTDH wild-type allele is located in the vicinity of 8q22.1 and is approximately 86 kb in length. This allele, which encodes protein LYRIC… 
National Institutes of Health

Related topics

Related topics

4 relations
8q22.1Protein LYRICTranscriptional Regulation

Broader (1)

MTDH gene

Papers overview

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Highly Cited
2015
Highly Cited
2015
EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway
The role of epidermal growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1) in osteosarcoma remains… 
Review
2013
Review
2013
AEG-1/MTDH/LYRIC, the beginning: initial cloning, structure, expression profile, and regulation of expression.
2011
2011
mRNA expression levels and genetic status of genes involved in the EGFR and NF-κB pathways in metastatic non-small-cell lung cancer patients
BackgroundMetastatic non-small-cell lung cancer (NSCLC) has a dismal prognosis. EGFR is overexpressed or mutated in a large… 
Highly Cited
2011
Highly Cited
2011
MTDH/AEG-1-based DNA vaccine suppresses lung metastasis and enhances chemosensitivity to doxorubicin in breast cancer
The gene MTDH/AEG-1 is overexpressed in more than 40% of breast cancer patients, and it is associated with poor clinical outcomes… 
2011
2011
Correlation of MTDH/AEG-1 and HOTAIR Expression with Metastasis and Response to Treatment in Sarcoma Patients.
BACKGROUND Chemoresistance and metastasis are the main reasons for the failure of current treatments with sarcoma patients. Novel… 
Highly Cited
2009
Highly Cited
2009
Knockdown of astrocyte elevated gene-1 inhibits proliferation and enhancing chemo-sensitivity to cisplatin or doxorubicin in neuroblastoma cells
BackgroundAstrocyte elevated gene-1 (AEG-1) was originally characterized as a HIV-1-inducible gene in primary human fetal… 
Highly Cited
2009
Highly Cited
2009
LYRIC/AEG-1 Is Targeted to Different Subcellular Compartments by Ubiquitinylation and Intrinsic Nuclear Localization Signals
Purpose: LYRIC/AEG-1 has been reported to influence breast cancer survival and metastases, and its altered expression has been… 
2009
2009
AEG-1 expression in invasive ductal and lobular breast cancers and its relationship with prognostic parameters
The pathophysiological mechanisms underlying blood-brain barrier (BBB) disruption in preeclampsia/eclampsia have not been… 
Highly Cited
2008
Highly Cited
2008
LYRIC/AEG-1 overexpression modulates BCCIPalpha protein levels in prostate tumor cells.
Highly Cited
1992
Highly Cited
1992
Mouse submandibular glands express an androgen-regulated transcript encoding an acidic epididymal glycoprotein-like molecule
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