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MTDH gene

Known as: ASTROCYTE ELEVATED GENE 1, 3D3, AEG-1 
This gene is involved in the regulation of transcription.
National Institutes of Health

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MTDH wt Allele
Protein LYRICTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
MTDH promotes glioma invasion through regulating miR-130b-ceRNAs
Cell invasion is crucial for high mortality and recurrence rate in glioma. Epithelial-mesenchymal transition (EMT) is an… 
2016
2016
The Universal 3D3 Antibody of Human PODXL Is Pluripotent Cytotoxic, and Identifies a Residual Population After Extended Differentiation of Pluripotent Stem Cells.
Podocalyxin-like protein (PODXL) is a member of CD34 family proteins. It is the protein that carries many post-translational… 
Highly Cited
2015
Highly Cited
2015
miR-153 inhibits epithelial–mesenchymal transition by targeting metadherin in human breast cancer
Epithelial–mesenchymal transition (EMT) is a crucial step in epithelial cancer invasion and metastasis. miR-153 has been… 
2013
2013
Increased expression of metadherin protein predicts worse disease‐free and overall survival in laryngeal squamous cell carcinoma
Metadherin (MTDH) is involved in tumourigenesis and cancer progression in multiple human malignancies. However, the MTDH protein… 
2013
2013
Metadherin Is a Prognostic Predictor of Hepatocellular Carcinoma after Curative Hepatectomy
Background/Aims The prognosis after surgical resection of hepatocellular carcinoma (HCC) remains poor because of a high rate of… 
2012
2012
Prognostic impact of Metadherin–SND1 interaction in colon cancer
The interaction between Metadherin (MTDH) and Staphylococcal nuclease homology domain containing 1 (SND1) is involved in… 
2012
2012
Clinical implications of AEG-1 in liver metastasis of colorectal cancer
The aim of the study was to investigate the role of AEG-1 in colorectal cancer and the relationship between AEG-1 protein… 
2012
2012
Metadherin Contributes to the Pathogenesis of Diffuse Large B-cell Lymphoma
Background Metadherin (MTDH) has been demonstrated as a potentially crucial mediator of various types of human malignancies… 
Highly Cited
2009
Highly Cited
2009
LYRIC/AEG-1 Is Targeted to Different Subcellular Compartments by Ubiquitinylation and Intrinsic Nuclear Localization Signals
Purpose: LYRIC/AEG-1 has been reported to influence breast cancer survival and metastases, and its altered expression has been… 
2008
2008
MTDH Activation by 8 q 22 Genomic Gain Promotes Chemoresistance and Metastasis of Poor-Prognosis Breast Cancer
Guohong Hu,1 Robert A. Chong,1,6 Qifeng Yang,2,6,7 Yong Wei,1 Mario A. Blanco,1 Feng Li,1 Michael Reiss,3,4 Jessie L.-S. Au,5… 
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