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MTAP gene

Known as: S-methyl-5'-thioadenosine phosphorylase, Methylthioadenosine Phosphorylase Gene, MeSAdo PHOSPHORYLASE 
This gene plays a role in purine salvage.
National Institutes of Health

Related topics

Related topics

5 relations
5'-Methylthioadenosine phosphorylaseAmino Acid BiosynthesisNucleotide MetabolismS-Methyl-5'-Thioadenosine Phosphorylase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Study on the relationship between genetic variation of DNA methylation and heterosis in soybean leaves
In order to well understand the molecular basis of heterosis in soybean, the methylation-sensitive amplification polymorphism… 
2016
2016
Early Prediction of Persistent Organ Failure by Serum Angiopoietin-2 in Patients with Acute Pancreatitis
BackgroundBiomarkers for the early prediction of the severity of acute pancreatitis (AP) are urgently needed for clinical… 
2016
2016
Genetic and epigenetic diversity and structure of Phragmites australis from local habitats of the Songnen Prairie using amplified fragment length polymorphism markers.
The genetic and epigenetic diversity and structure of naturally occurring Phragmites australis populations occupying two… 
2012
2012
Increasing the therapeutic index of 5-fluorouracil and 6-thioguanine by targeting loss of MTAP in tumor cells
Methylthioadenosine phosphorylase (MTAP), a key enzyme in the catabolism of 5′-deoxy-5′-methylthioadenosine (MTA), catalyzes the… 
2009
2009
Mice heterozygous for germ-line mutations in methylthioadenosine phosphorylase (MTAP) die prematurely of T-cell lymphoma.
Large homozygous deletions of 9p21 that inactivate CDKN2A, ARF, and MTAP are common in a wide variety of human cancers. The role… 
2009
2009
[Expression of methylthioadenosine phosphorylase (MTAP) gene and demethylation of its promoter in human colorectal cancer].
BACKGROUND AND OBJECTIVE Abnormal expression of 5'-methylthioadenosine phosphorylase (MTAP) is found in various tumor tissues… 
2005
2005
A combination of molecular cytogenetic analyses reveals complex genetic alterations in conventional renal cell carcinoma.
2004
2004
MSAP, the Meichroacidin Homolog of Carp (Cyprinus carpio), Differs from the Rodent Counterpart in Germline Expression and Involves Flagellar Differentiation
Abstract To gain access to the molecular mechanisms of spermatogenesis, the genes from a subtractive screen of the carp testis… 
2004
2004
Genetic identity of clones and methods to explore DNA.
Cloning by nuclear transfer has made it possible to produce genetically identical animals in terms of nuclear DNA content. Recent… 
Highly Cited
1996
Highly Cited
1996
Methylthioadenosine phosphorylase cDNA transfection alters sensitivity to depletion of purine and methionine in A549 lung cancer cells.
Methylthioadenosine phosphorylase (MTAP), an enzyme involved in purine and methionine metabolism, is present in all normal… 
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