Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

MSH2 gene

Known as: HNPCC, mutS homolog 2, MSH2 
This gene plays a role in DNA mismatch repair mutations in the gene result in hereditary nonpolyposis colorectal cancer-1.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Epimutations in the germline, such as methylation of the MLH1 gene, may contribute to hereditary cancer syndrome in human, but… Expand
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BACKGROUND Genetic testing to refine cancer risk is available. However, little is known about factors affecting the uptake of… Expand
  • table 1
  • table 2
  • table 2
  • table 3
  • table 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Forty-eight hereditary nonpolyposis colorectal carcinoma (HNPCC) families for which a tumor sample was available were evaluated… Expand
  • table 1
  • table 2
  • table 2
  • table 3
  • figure 1
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Hereditary nonpolyposis colorectal cancer (HNPCC) is caused by mutations in the mismatch-repair genes. We report here the… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
We investigated a possible role of the mismatch-repair gene MLH3 in hereditary nonpolyposis colorectal cancer by scanning for… Expand
  • table 1
  • figure 1
Is this relevant?
Review
2001
Review
2001
  • R. Fishel
  • Cancer research
  • 2001
  • Corpus ID: 3566616
The “mutator hypothesis” asserts that gene alterations that increase the rate of spontaneous mutation (mutators) underlie… Expand
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Hereditary non-polyposis colorectal cancer (HNPCC) is a common autosomal dominant condition characterized by early onset… Expand
  • figure 2
  • table 1
  • table 2
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Saccharomyces cerevisiae encodes six genes, MSH1-6, which encode proteins related to the bacterial MutS protein. In this study… Expand
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Germ line mutations in DNA mismatch repair genes including MLH1 cause hereditary nonpolyposis colon cancer. To understand the… Expand
  • figure 1
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
1994
Highly Cited
1994
The international collaborative group on HNPCC (ICG-HNPCC) was established in 1989. The original aims of the group were: (1) to… Expand
Is this relevant?