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MSH2 wt Allele

Known as: HNPCC1, COCA1, HNPCC 
Human MSH2 wild-type allele is located within 2p22-p21 and is approximately 80 kb in length. This allele, which encodes DNA mismatch repair protein… 
National Institutes of Health

Related topics

Related topics

12 relations
2p22-p21Colorectal cancer, hereditary nonpolyposis, type 1DNA RepairHereditary Nonpolyposis Colorectal Cancer

Broader (1)

MSH2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
MutS HOMOLOG1 Is a Nucleoid Protein That Alters Mitochondrial and Plastid Properties and Plant Response to High Light[W][OA]
This work provides evidence, using genetic perturbation of the MSH1 nuclear gene in five plant species, that MSH1 functions… 
Highly Cited
2010
Highly Cited
2010
MutS Homologue 2 and the Long-term Benefit of Adjuvant Chemotherapy in Lung Cancer
Purpose: We sought to determine the long-term (median follow-up, 7.5 years) predictive power of human MutS homologue 2 (MSH2… 
Highly Cited
2010
Highly Cited
2010
Extensive Rearrangement of the Arabidopsis Mitochondrial Genome Elicits Cellular Conditions for Thermotolerance1[W][OA]
Three nuclear genes involved in plant mitochondrial recombination surveillance have been previously identified. Simultaneous… 
Highly Cited
2007
Highly Cited
2007
Electrocatalysis on bimetallic surfaces: modifying catalytic reactivity for oxygen reduction by voltammetric surface dealloying.
We report a synthetic electrochemical strategy to deliberately modify the catalytic reactivity of Pt bimetallic surfaces. The… 
2006
2006
Fck1, a C-type cyclin-dependent kinase, interacts with Fcc1 to regulate development and secondary metabolism in Fusarium verticillioides.
Highly Cited
2001
Highly Cited
2001
Regulation of Fumonisin B1 Biosynthesis and Conidiation in Fusarium verticillioides by a Cyclin-Like (C-Type) Gene, FCC1
ABSTRACT Fumonisins are a group of mycotoxins produced in corn kernels by the plant-pathogenic fungus Fusarium verticillioides. A… 
Highly Cited
2000
Highly Cited
2000
Somatic Hypermutation in Muts Homologue (Msh)3-, Msh6-, and Msh3/Msh6-Deficient Mice Reveals a Role for the Msh2–Msh6 Heterodimer in Modulating the Base Substitution Pattern
Although the primary function of the DNA mismatch repair (MMR) system is to identify and correct base mismatches that have been… 
Highly Cited
1993
Highly Cited
1993
Identification of hereditary nonpolyposis colorectal cancer in the general population. The 6‐year experience of a population‐based registry
Background. Hereditary nonpolyposis colorectal cancer (HNPCC or Lynch syndrome) is an autosomal dominant disease characterized by… 
Highly Cited
1988
Highly Cited
1988
Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro
The fluoroquinolone antibiotics are structurally related to nalidixic acid. Their primary antibacterial action appears to be… 
Highly Cited
1983
Highly Cited
1983
Lack of cross-resistance to 4-aminoquinolines in chloroquine-resistant Plasmodium falciparum in vitro.
The potencies of 10 quinoline-containing antimalarials, including chloroquine, amodiaquine, CM-2,999-2K, quinine, mefloquine, SN… 
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