MRGPRX2 gene

Known as: MAS-Related GPR, Member X2 Gene, MAS related GPR family member X2, MRGPRX2 
This gene plays a role in both G protein-coupled receptor signaling and mast cell activation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2017
05101519772017

Papers overview

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2017
2017
The primate-exclusive MRGPRX2 G protein-coupled receptor (GPCR) has been suggested to modulate pain and itch. Despite putative… (More)
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2017
2017
 
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2016
2016
We present 3 cases of pseudoallergic (anaphylactoid) reactions to perioperatively administered rocuronium, which rapidly resolved… (More)
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Highly Cited
2015
Highly Cited
2015
Mast cells are primary effectors in allergic reactions, and may have important roles in disease by secreting histamine and… (More)
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2011
2011
Although human mast cells express G protein coupled receptors for the anaphylatoxin C3a, previous studies indicated that C3a… (More)
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2006
2006
Recently, a large family of G-protein-coupled receptors called Mas-related genes (Mrgs), which is selectively expressed in small… (More)
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2006
2006
Ghrelin, a natural GH secretagogue (GHS) acylated peptide, and cortistatin (CST), a natural SRIF-like peptide, interfere with… (More)
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2005
2005
Proadrenomedullin N-terminal 20 peptide (PAMP[1-20]/PAMP-20) and its truncated analog, PAMP[9-20]/PAMP-12, are endogenous… (More)
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2005
2005
MRGX2, a G-protein-coupled receptor, is specifically expressed in the sensory neurons of the human peripheral nervous system and… (More)
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Highly Cited
2003
Highly Cited
2003
MrgX2 is a recently identified orphan G-protein-coupled receptor whose ligand and physiological function were unknown. Here we… (More)
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