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MMP14 protein, human
Known as:
MMP-14
, Membrane-Type-1 Matrix Metalloproteinase
, membrane-type 1 matrix metalloproteinase, human
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Matrix metalloproteinase-14 (582 aa, ~66 kDa) is encoded by the human MMP14 gene. This protein is involved in both extracellular matrix proteolysis…
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National Institutes of Health
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Related topics
Related topics
13 relations
BMS-275291
Enzyme Gene
Hydrolysis
Inhibition of Matrix Metalloproteinases Pathway
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Broader (1)
membrane-type 1 matrix metalloproteinase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage…
E. Tchetina
,
Ginette Squires
,
A. Poole
Journal of Rheumatology
2005
Corpus ID: 22418905
OBJECTIVE Articular cartilage degeneration in osteoarthritis (OA) involves excessive degradation of extracellular matrix (ECM…
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Highly Cited
2004
Highly Cited
2004
Matrix Metalloproteinase/Tissue Inhibitors of Matrix Metalloproteinase Phenotype Identifies Poor Prognosis Colorectal Cancers
S. Curran
,
S. R. Dundas
,
J. Buxton
,
M. F. Leeman
,
Robin Ramsay
,
G. Murray
Clinical Cancer Research
2004
Corpus ID: 25581801
Purpose: The matrix metalloproteinases (MMPs) are a family of proteolytic enzymes involved in tumor invasion; several individual…
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Review
2003
Review
2003
MT1-MMP and MMP-7 in invasion and metastasis of human cancers
T. Shiomi
,
Y. Okada
Cancer Metastasis Review
2003
Corpus ID: 2738063
Previous experimental and biochemical studies on matrix metalloproteinases (MMPs) have indicated that MMPs are implicated in…
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Highly Cited
2001
Highly Cited
2001
Tumor gelatinases and invasion inhibited by the green tea flavanol epigallocatechin‐3‐gallate
S. Garbisa
,
L. Sartor
,
S. Biggin
,
B. Salvato
,
R. Benelli
,
A. Albini
Cancer
2001
Corpus ID: 25184947
Given the association of consumption of green tea with prevention of cancer development, metastasis, and angiogenesis, the effect…
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Highly Cited
2001
Highly Cited
2001
Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis
Aixiang Jiang
,
K. Lehti
,
Xing Wang
,
S. Weiss
,
J. Keski‐oja
,
D. Pei
Proceedings of the National Academy of Sciences…
2001
Corpus ID: 24792032
Membrane-type matrix metalloproteinase 1 (MT1-MMP) plays a critical role in extracellular matrix remodeling under both…
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Highly Cited
2001
Highly Cited
2001
Rac1 Mediates Type I Collagen-dependent MMP-2 Activation
Y. Zhuge
,
Jiahua Xu
Journal of Biological Chemistry
2001
Corpus ID: 42434306
Cell migration and proteolysis are two essential processes during tumor invasion and metastasis. Matrix metalloproteinase (MMP)-2…
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Highly Cited
2001
Highly Cited
2001
Increased extracellular matrix remodeling is associated with tumor progression in human hepatocellular carcinomas
N. Théret
,
O. Musso
,
+5 authors
B. Clement
Hepatology
2001
Corpus ID: 31665794
Matrix metalloproteinase‐2 (MMP2) is a key enzyme in the process of extracellular matrix remodeling involved in tumor invasion…
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Highly Cited
2000
Highly Cited
2000
Binding of Active (57 kDa) Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) to Tissue Inhibitor of Metalloproteinase (TIMP)-2 Regulates MT1-MMP Processing and Pro-MMP-2 Activation*
Sonia Hernandez-Barrantes
,
M. Tóth
,
+5 authors
R. Fridman
Journal of Biological Chemistry
2000
Corpus ID: 23726740
Previous studies have shown that membrane type 1-matrix metalloproteinase (MT1-MMP) (MMP-14) initiates pro-MMP-2 activation in a…
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Highly Cited
1999
Highly Cited
1999
Expression of MMP‐2 and MMP‐9, their inhibitors, and the activator MT1‐MMP in primary breast carcinomas
J. L. Jones
,
P. Glynn
,
R. Walker
Journal of Pathology
1999
Corpus ID: 30885285
Enhanced expression of the type IV collagenases MMP‐2 and MMP‐9, or lack of their inhibitors TIMP‐1 and TIMP‐2, has been…
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Highly Cited
1998
Highly Cited
1998
Proteolytic processing of membrane-type-1 matrix metalloproteinase is associated with gelatinase A activation at the cell surface.
K. Lehti
,
J. Lohi
,
Heli Valtanen
,
J. Keski‐oja
Biochemical Journal
1998
Corpus ID: 36429567
Human fibroblasts and HT-1080 fibrosarcoma cells express membrane-type-1 matrix metalloproteinase (MT1-MMP), the cell surface…
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