Skip to search formSkip to main contentSkip to account menu

MLLT10 gene

Known as: MLLT10, MYELOID/LYMPHOID OR MIXED LINEAGE LEUKEMIA, TRANSLOCATED TO, 10, ALL1-FUSED GENE FROM CHROMOSOME 10 
This gene may be involved in transcriptional regulation.
National Institutes of Health

Related topics

Related topics

6 relations
Homo sapiensMLL-AF10 Fusion Protein ExpressionProtein AF-10Transcriptional Regulation

Narrower (1)

MLLT10 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL
For children and young adults with T-lineage acute lymphoblastic leukemia (T-ALL), event free survival following relapse is < 10… 
2010
2010
Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice.
The t(10;11) translocation results in a CALM-AF10 fusion gene in a subset of leukemia patients. Expression of a CALM-AF10… 
2007
2007
AF10‐dependent transcription is enhanced by its interaction with FLRG
Background information. FLRG (follistatin‐related gene) is a secreted glycoprotein which is very similar to follistatin. As… 
2005
2005
Cryptic MLL-AF10 fusion caused by insertion of duplicated 5' part of MLL into 10p12 in acute leukemia: a case report.
2001
2001
Molecular analysis of the genomic inversion and insertion of AF10 into MLL suggests a single‐step event
The interstitial insertion of genetic material from one chromosome into another can achieve the type of gene–gene fusions more… 
2000
2000
Cytogenetic and molecular evidence of marrow involvement in extramedullary acute myeloid leukaemia
A diagnosis of granulocytic sarcoma was made in a 2‐year‐old child based on the detection of myelomonocytic blasts in tissue… 
1998
1998
Alternative splicing in wild-type AF10 and CALM cDNAs and in AF10-CALM and CALM-AF10 fusion cDNAs produced by the t(10;11)(p13–14;q14–q21) suggests a potential role for truncated AF10 polypeptides
The t(10;11)(p13;q14–21) is a non-random translocation that occurs primarily in T cell acute lymphoblastic leukemias (T-ALL), but… 
1997
1997
A novel MLL-AF10 fusion mRNA variant in a patient with acute myeloid leukemia detected by a new asymmetric reverse transcription PCR method
A novel variant of the chimerical MLL-AF10 mRNA transcript was detected in a pediatric patient with acute myeloid leukemia (AML… 
1996
1996
AF10 is split by MLL and HEAB, a human homolog to a putative Caenorhabditis elegans ATP/GTP-binding protein in an invins(10;11)(p12;q23q12).
Invins(10;11)(p12;q23q12) is one of the rare but recurring chromosome rearrangements seen in acute monoblastic leukemia. We… 
1995
1995
A novel type of MLL/AF10 fusion transcript in a child with acute megakaryocytic leukemia (AML-M7)
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)