Protein AF-10

Known as: ALL1-Fused Gene from Chromosome 10 Protein, MLLT10 
Protein AF-10 (1027 aa, ~109 kDa) is encoded by the human MLLT10 gene. This protein may be involved in the modulation of transcription.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2017
0120042017

Papers overview

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2018
2018
T-lineage ALL is an aggressive disease that needs to be treated with intensive treatment schedules. A late relapse rarely occurs… (More)
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2015
2015
Cytogenetic classification of acute lymphoblastic leukemia (ALL) is primarily based on numerical and structural chromosomal… (More)
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2013
2013
The MLLT10 gene, located at 10p13, is a known partner of MLL and PICALM in specific leukemic fusions generated from recurrent… (More)
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2013
2013
Complex rearrangements involving the MLL gene on chromosome 11q23 and MLLT10 on 10p have been reported in 15% of pediatric… (More)
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2012
2012
The PICALM-MLLT10 fusion gene, generated by the t(10;11)(p12-13;q14-21) translocation, is a rare but recurrent event in acute… (More)
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Review
2010
Review
2010
Patients with various hematologic malignancies, including acute lymphoblastic leukemia (ALL), acute myeloblastic leukemia (AML… (More)
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2007
2007
known as MLLT10) genes is common in acute megakaryoblastic leukemia (AMKL) in children without Down’s syndrome (DS), which was… (More)
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2006
2006
The t(9;22)(q34;q11) translocation occurs in chronic myeloid leukemia (CML) and adult B-cell acute lymphoblastic leukemia (ALL… (More)
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2005
2005
Hematologic malignancies are characterized by fusion genes of biological/clinical importance. Immortalized cell lines with such… (More)
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Review
2004
Review
2004
Cytogenetic studies of acute monoblastic leukemia cases presenting MLL-MLLT10 (alias MLL-AF10) fusion show a broad heterogeneity… (More)
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