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MLLT10 wt Allele

Known as: DKFZp686E10210, AF10, Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated To, 10 wt Allele 
Human MLLT10 wild-type allele is located in the vicinity of 10p12 and is approximately 209 kb in length. This allele, which encodes protein AF-10… 
National Institutes of Health

Related topics

Related topics

5 relations
10p12Homo sapiensTranscriptional Regulationdna binding

Broader (1)

MLLT10 gene

Papers overview

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2010
2010
Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice.
The t(10;11) translocation results in a CALM-AF10 fusion gene in a subset of leukemia patients. Expression of a CALM-AF10… 
2007
2007
Characterization of graft-versus-leukemia responses in patients treated for advanced chronic lymphocytic leukemia with donor lymphocyte infusions after in vitro T-cell depleted allogeneic stem cell…
Characterization of graft-versus-leukemia responses in patients treated for advanced chronic lymphocytic leukemia with donor… 
2007
2007
AF10‐dependent transcription is enhanced by its interaction with FLRG
Background information. FLRG (follistatin‐related gene) is a secreted glycoprotein which is very similar to follistatin. As… 
2006
2006
Genetics of resistance to 3 isolates of Ascochyta fabae on Faba bean (Vicia faba L.) in controlled conditions
SummaryGenetics of resistance to Ascochyta fabae Speg. in Vicia faba L. was studied with a final objective to develop resistant… 
2005
2005
Cryptic MLL-AF10 fusion caused by insertion of duplicated 5' part of MLL into 10p12 in acute leukemia: a case report.
2003
2003
Cytogenetics, fluorescence in situ hybridization, and reverse transcriptase polymerase chain reaction are necessary to clarify the various mechanisms leading to an MLL-AF10 fusion in acute myelocytic…
2001
2001
Molecular analysis of the genomic inversion and insertion of AF10 into MLL suggests a single‐step event
The interstitial insertion of genetic material from one chromosome into another can achieve the type of gene–gene fusions more… 
1998
1998
Alternative splicing in wild-type AF10 and CALM cDNAs and in AF10-CALM and CALM-AF10 fusion cDNAs produced by the t(10;11)(p13–14;q14–q21) suggests a potential role for truncated AF10 polypeptides
The t(10;11)(p13;q14–21) is a non-random translocation that occurs primarily in T cell acute lymphoblastic leukemias (T-ALL), but… 
1998
1998
A human B cell line AF10 expressing hIL‐17
AF10, a human B cell line, is a mycoplasma‐free variant cloned from the human IgE myeloma cell line U266. Total RNA isolated from… 
1996
1996
AF10 is split by MLL and HEAB, a human homolog to a putative Caenorhabditis elegans ATP/GTP-binding protein in an invins(10;11)(p12;q23q12).
Invins(10;11)(p12;q23q12) is one of the rare but recurring chromosome rearrangements seen in acute monoblastic leukemia. We… 
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