MK-422

Known as: MK 422, MK422 
 

Topic mentions per year

Topic mentions per year

1982-2005
0102019822005

Papers overview

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1990
1990
MK-422 (enalaprilat) (0.0005-0.5%) significantly reduced intraocular pressure (IOP) in African Green monkeys. Studies utilizing… (More)
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1987
1987
There have recently been reports of persistent cough and increased broncho-obstruction likely to have been induced by ACE… (More)
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1987
1987
The antihypertensive effect of enalaprilat (MK-422), an intravenous (IV), nonsulfhydryl converting-enzyme inhibitor, was… (More)
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Highly Cited
1984
Highly Cited
1984
Endopeptidase-24.11 (EC 3.4.24.11), purified to homogeneity from pig kidney, was shown to hydrolyse a wide range of neuropeptides… (More)
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1984
1984
The hydrolysis of substance P is catalyzed by purified rabbit lung angiotensin-converting enzyme (peptidyldipeptide hydrolase, EC… (More)
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1984
1984
The effect of captopril, MK-421 and MK-422 on fibrinolysis was investigated in vitro with 3 assay methods. Incorporation of… (More)
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1984
1984
The angiotensin-converting enzyme (ACE) inhibitor MK-422 (enalaprilat) was compared with the potent renin inhibitor SCRIP for its… (More)
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1984
1984
Intracerebroventricular (i.c.v.) administration of captopril attenuates the development of hypertension in spontaneously… (More)
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1983
1983
In hypertensive patients the time courses for the rise in serum MK-422 level, and fall in both angiotensin converting enzyme (ACE… (More)
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1982
1982
1 The disposition of two angiotensin converting-enzyme inhibitor drugs was studied in normal volunteers. One drug was enalapril… (More)
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