Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

MK-422

Known as: MK 422, MK422 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1990
1990
MK-422 (enalaprilat) (0.0005-0.5%) significantly reduced intraocular pressure (IOP) in African Green monkeys. Studies utilizing… Expand
1988
1988
Nineteen mongrel dogs had 30 minutes of thoracic aortic occlusion to determine the effects that blockade of the renin-angiotensin… Expand
1986
1986
The acute hemodynamic and hormonal effects of the oral angiotensin-converting enzyme (ACE) inhibitor lisinopril (MK-521) were… Expand
1986
1986
The spontaneously hypertensive rat (SHR) has many characteristics indicative of an overactive brain-angiotensin system. Since… Expand
1985
1985
The in vitro conversion of enalapril (MK421) to enalaprilic acid (MK422) in human autopsy tissues was examined. MK422 was… Expand
  • figure 1
Highly Cited
1984
Highly Cited
1984
Endopeptidase-24.11 (EC 3.4.24.11), purified to homogeneity from pig kidney, was shown to hydrolyse a wide range of neuropeptides… Expand
Highly Cited
1984
Highly Cited
1984
The hydrolysis of substance P is catalyzed by purified rabbit lung angiotensin-converting enzyme (peptidyldipeptide hydrolase, EC… Expand
1983
1983
In hypertensive patients the time courses for the rise in serum MK-422 level, and fall in both angiotensin converting enzyme (ACE… Expand
Highly Cited
1983
Highly Cited
1983
  • E. Ulm
  • Drug metabolism reviews
  • 1983
  • Corpus ID: 23369291
Animal studies (particularly in dogs) on enalapril maleate have served to predict the patterns of absorption and elimination… Expand
Highly Cited
1982
Highly Cited
1982
1 The disposition of two angiotensin converting-enzyme inhibitor drugs was studied in normal volunteers. One drug was enalapril… Expand