Enalaprilat

Known as: Enalaprilat [Chemical/Ingredient], N-(1(S)-Carboxy-3-phenylpropyl)-L-alanyl-L-proline, N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline-water (1/2) 
The active metabolite of the pro-drug enalapril, a dicarboxylate-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2018
0204019842018

Papers overview

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2004
2004
Angiotensin converting enzyme (ACE) plays a critical role in the circulating or endocrine renin-angiotensin system (RAS) as well… (More)
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2002
2002
Enalaprilat is a typical angiotensin-converting enzyme inhibitor and is very poorly absorbed from the gastrointestinal tract. The… (More)
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2001
2001
In vitro characteristics of the human erythrocytes loaded by enalaprilat have been evaluated. Erythrocytes obtained from a… (More)
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Highly Cited
2000
Highly Cited
2000
A novel human zinc metalloprotease that has considerable homology to human angiotensin-converting enzyme (ACE) (40% identity and… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Survival of post-myocardial infarction patients is related inversely to their levels of very-low-frequency (0.003 to 0… (More)
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1998
1998
BACKGROUND Chronic heart failure (CHF) is associated with endothelial dysfunction, including impaired flow-dependent (endothelium… (More)
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Highly Cited
1996
Highly Cited
1996
OBJECTIVES This study sought to determine the effects of enalaprilat on reflex control of sympathetic nerve activity… (More)
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Highly Cited
1993
Highly Cited
1993
It is now established that all of the components necessary for the local formation of angiotensin II (ANG II) coexist in the… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND Long-term administration of angiotensin-converting--enzyme (ACE) inhibitors has been shown to improve survival in… (More)
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1984
1984
Enalaprilat (MK-422), a new and potent angiotensin- converting enzyme inhibitor, and its monoethyl ester precursor, enalapril… (More)
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