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MK 383

Known as: MK-383 
National Institutes of Health

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TIROFIBAN HYDROCHLORIDE

Broader (1)

tirofiban

Papers overview

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2005
2005
1994 American Heart Association Scientific Sessions at a Glance
9 Activation of platelets induced by coronary angioplasty is inhibited by S-nitrosoglutathione. Langford E J, 1-552. 9 Angioscopy… 
2002
2002
MK-383 (Tirofiban) induces a GPIIb/IIIa receptor conformation which differs from the resting and activated receptor
The platelet integrin αIIb β3 (GPIIb/IIIa) acts as a receptor for fibrinogen, playing a critical role in platelet aggregation… 
Review
2002
Review
2002
Le tirofiban : une nouvelle force d'intervention puissante contre l'angine instable et l'infarctus du myocarde sans onde Q
Resume Cet article est une analyse documentaire sur la pharmacologie et les etudes multicentriques realisees avec le tirofiban… 
2000
2000
Integrin a IIb b 3 Inhibitor Preserves Microvascular Patency in Experimental Acute Focal Cerebral Ischemia
Background and Purpose —Platelets become activated and accumulate in brain microvessels of the ischemic microvascular bed after… 
1999
1999
Correlation between the in vivoEff icacy of GPIIb/IIIa Receptor Antagonists (m7E3, MK-383 and DMP-728) and ex vivo Platelet Inhibition
In vivo antithrombotic efficacy of GPIIb/IIIa receptor antagonists (m7E3, MK-383 and DMP-728) was studied with respect to their… 
1998
1998
Protection of platelet glycoprotein IIb/IIIa receptor complex preserves platelet function during in vitro ventricular assisted circulation.
Platelet dysfunction probably contributes to bleeding associated with ventricular assist devices (VADs). Previous evidence… 
1998
1998
Platelet glycoprotein IIb/IIIa inhibitor attenuates complement activation during in vitro ventricular assist circulation.
Complement activity and platelet glycoprotein (GP) IIb/IIIa dysfunction have been demonstrated during in vitro ventricular assist… 
1994
1994
Antibodies join the anticoagulant army
Linking antifibrin antibodies with plasminogen activators or antithrombotic drugs is an exciting new approach in the quest to… 
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