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TIROFIBAN HYDROCHLORIDE

Known as: N-(Butylsulfonyl)-O-(4-(4-piperidinyl)butyl)-L-tyrosine Monohydrochloride 
The hydrochloride salt form of tirofiban, a non-peptide tyrosine derivative with anticoagulant property. Tirofiban antagonizes fibrinogen binding to… 
National Institutes of Health

Related topics

Related topics

16 relations
15 ML tirofiban 0.25 MG/ML Injection [Aggrastat]AneurysmAngina, UnstableCongenital arteriovenous malformation

Narrower (2)

Aggrastattirofiban hydrochloride monohydrate

Broader (1)

tirofiban

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Comparison on Anticoagulation and Antiplatelet Aggregation Effects of Puerarin with Heparin Sodium and Tirofiban Hydrochloride: An In Vitro Study
ObjectiveTo detect the anticoagulation and antiplatelet effects of different concentrations of puerarin, heparin sodium and… 
2016
2016
Development of alternative HPLC method for determination of tirofiban in rat serum
Tirofiban hydrochloride is a reversible antagonist of fibrinogen binding to the GPIIb/IIIa receptor, used for the treatment of… 
2013
2013
[The clinical efficacy and safety of fondaparinux combined with tirofiban hydrochloride in patients with acute coronary syndrome undergoing complex percutaneous coronary intervention].
OBJECTIVE To explore the efficacy and safety of fondaparinux combined with tirofiban in patients with high risk unstable angina… 
2012
2012
THE EFFECT OF TIROFIBAN HYDROCHLORIDE ON SERUM HS-CRP LEVEL IN PATIENTS WITH ACUTE CORONARY SYNDROME
Objectives To analysis the hs-CRP concentrations in patients with acute coronary syndrome before and after hydrochloride… 
2009
2009
The GPIIbIIIa antagonist drugs eptifibatide and tirofiban do not induce activation of apoptosis executioner caspase-3 in resting platelets but inhibit caspase-3 activation in platelets stimulated…
Platelet surface receptor, glycoprotein (GP) IIbIIIa (integrin αIIbβ3), mediates platelet aggregation and plays a key role in… 
2003
2003
Spontaneous acute coronary dissection after cocaine abuse in a young woman.
Spontaneous coronary artery dissection is an unusual trigger for acute coronary syndrome or sudden death, occurring more… 
Review
2002
Review
2002
Gateways to Clinical Trials. June 2002.
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… 
Review
2001
Review
2001
Stability and compatibility of tirofiban hydrochloride during simulated Y-site administration with other drugs.
The stability and compatibility of tirofiban hydrochloride injection during simulated Y-site administration with various other… 
1999
1999
In vitro and in vivo studies on the metabolism of tirofiban.
Tirofiban hydrochloride [L-tyrosine-N-(butylsulfonyl)-O-[4-(4-piperidinebutyl)] monohydrochloride, is a potent and specific… 
1997
1997
Use of LC-MS/MS to cross-validate a radioimmunoassay for the fibrinogen receptor antagonist, Aggrastat (tirofiban hydrochloride) in human plasma.
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