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MIR221 wt Allele

Known as: Micro RNA 221 Gene, MIRN221, miRNA221 
Human MIR221 wild-type allele is located in the vicinity of Xp11.3 and is 109 bases in length. This allele, which encodes the MIR221 pre-miRNA, plays… 
National Institutes of Health

Related topics

Related topics

12 relations
Breast CarcinomaCarcinoma of lungEpithelial ovarian cancerGlioblastoma

Broader (1)

MIR221 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Expression of microRNAs, miR‐21, miR‐31, miR‐122, miR‐145, miR‐146a, miR‐200c, miR‐221, miR‐222, and miR‐223 in patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma and its…
MicroRNAs are a class of non‐coding molecules found to regulate a variety of cellular functions in health and disease… 
Highly Cited
2011
Highly Cited
2011
MicroRNA expression analysis in triple-negative (ER, PR and Her2/neu) breast cancer
miRNAs are small, regulatory molecules approximately 21-24 nucleotides in length. They function at the post-transcriptional level… 
Highly Cited
2011
Highly Cited
2011
miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1.
Dendritic cells (DCs) are potent antigen-presenting cells derived from hematopoietic progenitor cells and circulating monocytes… 
Highly Cited
2010
Highly Cited
2010
microRNA Expression Patterns Reveal Differential Expression of Target Genes with Age
Recent evidence supports a role for microRNAs (miRNAs) in regulating the life span of model organisms. However, little is known… 
Highly Cited
2010
Highly Cited
2010
MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN
BackgroundMicroRNAs (miRNAs) can function as either oncogenes or tumor suppressor genes via regulation of cell proliferation and… 
Highly Cited
2010
Highly Cited
2010
A Pumilio-induced RNA structure switch in p27-3′ UTR controls miR-221 and miR-222 accessibility
Key regulators of 3′ untranslated regions (3′ UTRs) are microRNAs and RNA-binding proteins (RBPs). The p27 tumour suppressor is… 
Highly Cited
2010
Highly Cited
2010
MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma
BackgroundMiR-221 and miR-222 (miR-221/222) are frequently up-regulated in various types of human malignancy including… 
Highly Cited
2010
Highly Cited
2010
Circulating miR‐221 directly amplified from plasma is a potential diagnostic and prognostic marker of colorectal cancer and is correlated with p53 expression
Background and Aim:  Circulating miRNAs exist in serum and plasma and they can be used as a potential noninvasive molecular… 
Highly Cited
2009
Highly Cited
2009
MicroRNA-221 Targets Bmf in Hepatocellular Carcinoma and Correlates with Tumor Multifocality
Deregulated cell proliferation and apoptosis play a major role in hepatocellular carcinoma (HCC). MicroRNAs participate in the… 
Highly Cited
2009
Highly Cited
2009
Evidence for Selective microRNAs and Their Effectors as Common Long-Term Targets for the Actions of Mood Stabilizers
MicroRNAs (miRNAs) regulate messenger RNA (mRNA) translation in a sequence-specific manner and are emerging as critical… 
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