MIR145 wt Allele

Known as: MIRN145, miRNA145, mir-145 
Human MIR145 wild-type allele is located in the vicinity of 5q33.1 and is 87 bases in length. This allele, which encodes MIR145 pre-miRNA, plays a… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Invasion and metastasis are the major features of malignant tumors that are responsible for 90% of cancer-related deaths… (More)
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Highly Cited
2012
Highly Cited
2012
MiR-145 can regulate cell apoptosis, proliferation, neural development and stem cell differentiation. Previous studies indicate… (More)
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Highly Cited
2011
Highly Cited
2011
MicroRNAs (miRNA) aberrantly expressed in tumors may offer novel therapeutic approaches to treatment. miR-145 is downregulated in… (More)
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Highly Cited
2010
Highly Cited
2010
MicroRNAs are important gene regulators that could play a profound role in tumorigenesis. Our previous studies indicate that miR… (More)
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Highly Cited
2010
Highly Cited
2010
Understanding the consequences of miR-145 reintroduction in human breast cancer (BC) could reveal its tumor-suppressive functions… (More)
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Highly Cited
2010
Highly Cited
2010
MicroRNAs are important gene regulators that potentially play a profound role in tumorigenesis. Increasing evidence indicates… (More)
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Highly Cited
2009
Highly Cited
2009
Phenotypic modulation of vascular smooth muscle cells (VSMCs) plays a critical role in the pathogenesis of a variety of… (More)
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Highly Cited
2009
Highly Cited
2009
The tumor suppressor p53 negatively regulates a number of genes, including the proto-oncogene c-Myc, in addition to activating… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE Downregulation of specific microRNAs (miRNAs) occurs in human tumors, which suggests a function for miRNAs in tumor… (More)
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Highly Cited
2009
Highly Cited
2009
Vascular injury triggers dedifferentiation and cytoskeletal remodeling of smooth muscle cells (SMCs), culminating in vessel… (More)
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