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MGV Vaccine

Known as: GM2/GD2 gangliosides-KLH Vaccine 
A vaccine that contains the GM2 and GD2 antigens separately coupled to the carrier protein Keyhole Limpet Hemocyanin and mixed with QS-21 adjuvant… Expand
National Institutes of Health

Papers overview

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2013
2013
Detection of N-glycolyated gangliosides in non-small-cell lung cancer using GMR8 monoclonal antibody.
Gangliosides are glycosphingolipids found on the cell surface. They act as recognition molecules or signal modulators and… Expand
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2013
2013
Human antibodies reactive to NeuGcGM3 ganglioside have cytotoxic antitumor properties.
N-glycolylated gangliosides are not naturally expressed in healthy human tissues but are overexpressed in several tumors. We… Expand
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2012
2012
Racotumomab: an anti-idiotype vaccine related to N-glycolyl-containing gangliosides – preclinical and clinical data
Neu-glycolyl (NeuGc)-containing gangliosides are attractive targets for immunotherapy with anti-idiotype mAbs, because these… Expand
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2005
2005
Glycosphingolipid component profiles of human gliomas correlate with histological tumour types: Analysis of inter-individual and tumour-regional distribution
SummaryThree types of glycosphingolipid (GSL) component profiles have been established for human intracranial gliomas. GSL-type I… Expand
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2002
2002
A monoclonal antibody against NeuGc-containing gangliosides contains a regulatory idiotope involved in the interaction with B and T cells.
P3 (IgM-kappa) is a monoclonal antibody (mAb) reacting with N-glycolyl neuraminic acid (NeuGc)-containing gangliosides and… Expand
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1999
1999
Expression of mouse sialic acid on gangliosides of a human glioma grown as a xenograft in SCID mice.
Ganglioside sialic acid content was examined in the U87-MG human glioma grown as cultured cells and as a xenograft in severe… Expand
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1993
1993
CDw60 glycolipid antigens of human leukocytes: structural characterization and cellular distribution.
Monoclonal CDw60 antibodies recognize glycolipid antigens with restricted surface expression on human leukocytes. They allow us… Expand
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1993
1993
Characterization of ganglioside expression in human melanoma cells: immunological and biochemical analysis.
The expression of N-glycolylneuraminic acid (NeuGc)-containing gangliosides in human melanoma cells grown both in culture and as… Expand
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1991
1991
Humoral immune response in disease‐free advanced melanoma patients after vaccination with melanoma‐associated gangliosides
Several studies have shown that melanoma-associated gangliosides are immunogenic in melanoma patients and that antibodies against… Expand
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1985
1985
Characterization of N-glycolylneuraminic acid-containing gangliosides as tumor-associated Hanganutziu-Deicher antigen in human colon cancer.
Hanganutziu-Deicher (HD) antigen-active N-glycolylneuraminic acid (NeuGc)-containing gangliosides were isolated and characterized… Expand
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