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MGV Vaccine

Known as: GM2/GD2 gangliosides-KLH Vaccine 
A vaccine that contains the GM2 and GD2 antigens separately coupled to the carrier protein Keyhole Limpet Hemocyanin and mixed with QS-21 adjuvant… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Detection of N‐glycolyated gangliosides in non‐small‐cell lung cancer using GMR8 monoclonal antibody
Gangliosides are glycosphingolipids found on the cell surface. They act as recognition molecules or signal modulators and… Expand
2012
2012
Racotumomab: an anti-idiotype vaccine related to N-glycolyl-containing gangliosides – preclinical and clinical data
Neu-glycolyl (NeuGc)-containing gangliosides are attractive targets for immunotherapy with anti-idiotype mAbs, because these… Expand
Highly Cited
2006
Highly Cited
2006
Chemical and chemoenzymatic synthesis of S-linked ganglioside analogues and their protein conjugates for use as immunogens.
Analogues of the tumor-associated gangliosides GM(3) and GM(2) containing terminal S-linked neuraminic acid residues and an amino… Expand
2005
2005
Biosynthesis of conjugatable saccharidic moieties of GM2 and GM3 gangliosides by engineered E. coli.
Oligosaccharidic moieties of GM(2) and GM(3) gangliosides bearing an allyl or a propargyl aglycon, are efficiently biosynthesized… Expand
2002
2002
A monoclonal antibody against NeuGc-containing gangliosides contains a regulatory idiotope involved in the interaction with B and T cells.
P3 (IgM-kappa) is a monoclonal antibody (mAb) reacting with N-glycolyl neuraminic acid (NeuGc)-containing gangliosides and… Expand
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1993
1993
Characterization of ganglioside expression in human melanoma cells: immunological and biochemical analysis.
The expression of N-glycolylneuraminic acid (NeuGc)-containing gangliosides in human melanoma cells grown both in culture and as… Expand
1993
1993
CDw60 glycolipid antigens of human leukocytes: structural characterization and cellular distribution.
Monoclonal CDw60 antibodies recognize glycolipid antigens with restricted surface expression on human leukocytes. They allow us… Expand
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1991
1991
Isolation and structural elucidation of a novel type of ganglioside, deaminated neuraminic acid (KDN)-containing glycosphingolipid, from rainbow trout sperm. The first example of the natural…
Rainbow trout sperm contained almost exclusively monoanionic ganglioside fraction as a major acidic glycosphingolipid. Two… Expand
1991
1991
Humoral immune response in disease‐free advanced melanoma patients after vaccination with melanoma‐associated gangliosides
Several studies have shown that melanoma‐associated gangliosides are immunogenic in melanoma patients and that antibodies against… Expand
Highly Cited
1985
Highly Cited
1985
Characterization of N-glycolylneuraminic acid-containing gangliosides as tumor-associated Hanganutziu-Deicher antigen in human colon cancer.
Hanganutziu-Deicher (HD) antigen-active N-glycolylneuraminic acid (NeuGc)-containing gangliosides were isolated and characterized… Expand
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