FAQ

MGV Vaccine

Known as: GM2/GD2 gangliosides-KLH Vaccine 
A vaccine that contains the GM2 and GD2 antigens separately coupled to the carrier protein Keyhole Limpet Hemocyanin and mixed with QS-21 adjuvant… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
01219952017

Papers overview

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2017
2017
B-CD8+ T Cell Interactions in the Anti-Idiotypic Response against a Self-Antibody
P3 is a murine, germline, IgM mAb that recognizes N-glycolylated gangliosides and other self-antigens. This antibody is able to… (More)
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2015
2015
Therapeutic effects of intrathecal versus intravenous monosialoganglioside against bupivacaine-induced spinal neurotoxicity in rats.
BACKGROUND Bupivacaine causes neuronal and axonal degeneration, leading to cauda equina syndrome or permanent nerve damage. Our… (More)
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2015
2015
Anti-Ganglioside Antibodies in Amyotrophic Lateral Sclerosis Revisited
BACKGROUND Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disorder with typical onset in the 5th- 6th… (More)
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2014
2014
Efficient biotransformation of polysialogangliosides for preparation of GM1 by Cellulosimicrobium sp. 21.
A new ganglioside transformed strain isolated from soil was identified as Cellulosimicrobium sp. 21. It produced a sialidase… (More)
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2013
2013
Human antibodies reactive to NeuGcGM3 ganglioside have cytotoxic antitumor properties.
N-glycolylated gangliosides are not naturally expressed in healthy human tissues but are overexpressed in several tumors. We… (More)
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2008
2008
Anti-ganglioside antibody-induced tumor cell death by loss of membrane integrity.
Gangliosides have been involved in multiple cellular processes such as growth, differentiation and adhesion, and more recently as… (More)
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2007
2007
Gangliosides, Ab1 and Ab2 antibodies I. Towards a molecular dissection of an idiotype-anti-idiotype system.
This report is focused on the molecular basis for the interaction of a monoclonal antibody (mAb) and its anti-idiotypic mAb. P3… (More)
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2007
2007
GD3 Vaccines for Melanoma: Superior Immunogenicity of Keyhole Limpet Hemocyanin Conjugate Vaccines I
Cell surface gangliosides show altered patterns of expression as a consequence of malignant transformation and have therefore… (More)
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2006
2006
Chemical and chemoenzymatic synthesis of S-linked ganglioside analogues and their protein conjugates for use as immunogens.
Analogues of the tumor-associated gangliosides GM(3) and GM(2) containing terminal S-linked neuraminic acid residues and an amino… (More)
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2004
2004
Isolation and characterization of gangliosides from Trypanosoma brucei.
Gangliosides were isolated from Trypanosoma brucei and analyzed by thin-layer chromatography (TLC) and TLC immunostaining test… (More)
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