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MECOM wt Allele

Known as: Ecotropic Viral Integration Site 1 Gene, MGC163392, PRDM3 
Human MECOM wild-type allele is located within 3q24-q28 and is approximately 64 kb in length. This allele, which encodes MDS1 and EVI1 complex locus… 
National Institutes of Health

Related topics

Related topics

7 relations
3q26Evi-1 proteinHomo sapiensMAPK Signaling Pathway

Broader (1)

MECOM gene

Papers overview

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Review
2019
Review
2019
MECOM: A Very Interesting Gene Involved also in Lymphoid Malignancies.
OBJECTIVES The Ecotropic Viral Integration Site 1 gene (EVI1), also known as the MDS1 and EVI1 Complex Locus (MECOM), is located… 
2019
2019
A Randomized, Double-Blind, Placebo-Controlled, Phase II Study of MBG453 Added to Hypomethylating Agents (HMAs) in Patients (pts) with Intermediate, High, or Very High Risk Myelodysplastic Syndrome…
Background and Rationale: Pts with higher-risk (HR; intermediate, high, or very high risk) MDS experience poor outcomes and have… 
2016
2016
Acute myeloid leukemia with t(3;8)(q26;q24) complicated by diabetes insipidus
Dear Editor, Translocation (3;8)(q26;q24), involving the ecotropic viral integration site 1 gene (EVI1), is a very rare and… 
2014
2014
Multigene pathway‐based analyses identify nasopharyngeal carcinoma risk associations for cumulative adverse effects of TERT‐CLPTM1L and DNA double‐strand breaks repair
The genetic etiology of nasopharyngeal carcinoma (NPC) and mechanisms for inherited susceptibility remain unclear. To examine… 
2013
2013
EVI1 splice variants modulate functional responses in ovarian cancer cells
Review
2011
Review
2011
EVI1-MDS1/EVI1 (ecotropic viral integration site 1 (EVI1) and myelodysplastic syndrome 1 (MDS1)-EVI1)
Review on EVI1-MDS1/EVI1 (ecotropic viral integration site 1 (EVI1) and myelodysplastic syndrome 1 (MDS1)-EVI1), with data on DNA… 
2006
2006
MDS1-EVI1 and EVI1 Overexpression Results in Changes in the Behavior of Murine Hematopoietic Cells.
We have found non-random patterns of retroviral integration in long-term hematopoietic repopulating cells in the rhesus macaque… 
2001
2001
PRDI-BF 1 silences CIITA expression in multiple myeloma cells
The Major Histocompatibility Complex (MHC) class II transactivator (CIITA) acts as a master switch to activate expression of the… 
1998
1998
Comparative expression analysis of the antagonistic transcription factors EVI1 and MDS1-EVI1 in murine tissues and during in vitro hematopoietic differentiation.
An alternative form of the transcription factor EVI1, MDS1-EVI1, which previously had been believed to exist only in the context… 
1998
1998
[Study on expression of Evi1 and MDS1-Evi1 genes in myelodysplastic syndromes].
  • K. XuL. WangY. Hao
  • Zhonghua xue ye xue za zhi = Zhonghua xueyexue…
  • 1998
  • Corpus ID: 1320002
OBJECTIVE To investigate expression of Evi1 and MDS1-Evi1 genes in myelodysplastic syndromes (MDS) and its role in pathogenesis… 
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