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MDK gene

Known as: NEURITE GROWTH-PROMOTING FACTOR 2, FORMERLY, FLJ27379, NEGF2, FORMERLY 
This gene is involved in nervous tissue development. It plays a role in neuronal differentiation, growth, regeneration and survival.
National Institutes of Health

Related topics

Related topics

8 relations
Cell Proliferation Regulatory ProcessHomo sapiensMDK protein, humanNeurogenesis

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MDK wt Allelemidkine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Perspectives on a combined test of multi serum biomarkers in China: towards screening for and diagnosing hepatocellular carcinoma at an earlier stage.
China has 50% of the worldwide hepatocellular carcinoma (HCC) cases, and the HBV-related cases accounts for approximately 85… 
Highly Cited
2012
Highly Cited
2012
Searching for molecular targets in sarcoma.
2007
2007
Midkine is an autocrine activator of signal transducer and activator of transcription 3 in 3T3-L1 cells.
Mitotic clonal expansion is believed to be necessary for 3T3-L1 adipocyte formation. Signal transducer and activator of… 
2007
2007
Evaluation of expression of midkine in oral squamous cell carcinoma and its correlation with tumour angiogenesis.
Highly Cited
2001
Highly Cited
2001
Haptotactic Migration Induced by Midkine
Midkine, a heparin-binding growth factor, plays a critical role in cell migration causing suppression of neointima formation in… 
Highly Cited
1996
Highly Cited
1996
Midkine, a heparin-binding growth/differentiation factor, exhibits nerve cell adhesion and guidance activity for neurite outgrowth in vitro.
By means of a baculovirus expression system, a large amount of mouse midkine (MK) was produced. The protein was purified to… 
Review
1993
Review
1993
Midkine (MK), the product of a retinoic acid responsive gene, and pleiotrophin constitute a new protein family regulating growth and differentiation.
Using mouse teratocarcinoma system, we found a novel retinoic acid responsive gene. Midkine (MK), the product of the gene is a… 
Highly Cited
1992
Highly Cited
1992
Genomic structure of human midkine (MK), a retinoic acid-responsive growth/differentiation factor.
Midkine (MK) is a product of a retinoic acid-responsive gene and a new heparin-binding growth/differentiation factor. The coding… 
Highly Cited
1992
Highly Cited
1992
A new family of heparin binding growth/differentiation factors: differential expression of the midkine (MK) and HB-GAM genes during mouse development.
MK (midkine) and HB-GAM (heparin-binding growth-associated molecule) constitute a new family of heparin-binding growth… 
Highly Cited
1991
Highly Cited
1991
A new family of heparin-binding factors: strong conservation of midkine (MK) sequences between the human and the mouse.
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