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MDK protein, human

Known as: ARAP, neurite growth-promoting factor 2, human, Amphiregulin-Associated Protein 
Midkine (143 aa, ~16 kDa) is encoded by the human MDK gene. This protein plays a role in receptor signaling and the modulation of cell proliferation.
National Institutes of Health

Related topics

Related topics

11 relations
Binding ProteinsCell Proliferation Regulatory ProcessExtracellular SpaceGrowth Factor Gene

Broader (1)

Nerve Growth Factors

Papers overview

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2017
2017
Short-term extracellular glucose exposure alters neurite outgrowth and intracellular reactive oxygen species without altering viability in neuronal cells
Hyperglycemia is the main trigger for diabetic neuropathic pain and can cause degeneration of the sensory neurons. Here, we… 
2013
2013
Structure-function analysis of full-length midkine reveals novel residues important for heparin binding and zebrafish embryogenesis.
Midkine is a heparin-binding di-domain growth factor, implicated in many biological processes as diverse as angiogenesis… 
2009
2009
L-asparaginase and prednisolone pretreatment followed by rubidomycin and cytosine arabinoside for induction of remission in adult patients with acute myeloblastic leukaemia.
77 unselected adult patients with acute myeloblastic leukaemia (AML), including practically all AML patients from an area with 1… 
2007
2007
Serum midkine concentrations and gastric cancer
2006
2006
Immunoenzymatic Method for Midkine Determination in Serum
Background. Midkine is a secreted protein originally engaged in neurogenesis and recently reported to be impli− cated in… 
2005
2005
Postischemic gene transfer of midkine, a neurotrophic factor, protects against focal brain ischemia
1999
1999
Midkine is expressed during repair of bone fracture and promotes chondrogenesis
1998
1998
Clusters of Basic Amino Acids in Midkine: Roles in Neurite-promoting Activity and Plasminogen Activator-enhancing Activity(ミッドカイン分子内の塩基性アミノ酸のクラスター: 神経突起伸長促進とプラスミノーゲン活性化因子活性化におけるその役割)
1995
1995
Synthetic peptides derived from midkine enhance plasminogen activator activity in bovine aortic endothelial cells.
Chemically synthesized human midkine enhanced plasminogen activator activity and decreased its inhibitor levels in bovine aortric… 
1986
1986
Calcium fluxes activated during neurite spiking induced by bradykinin