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MCM7 gene

Known as: MCM7, MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 7, PPP1R104 
This gene is involved in the initiation and licensing of DNA replication. It also plays a role in cell cycle inhibition following DNA damage.
National Institutes of Health

Related topics

Related topics

7 relations
Cervix carcinomaDNA ReplicationDNA Replication Licensing Factor MCM7MCM7 protein, human

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MCM7 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Overexpression of G9a and MCM7 in oesophageal squamous cell carcinoma is associated with poor prognosis
Histone methyltransferase G9a has been primarily understood as a co‐repressor of gene expression, but it has been shown that G9a… 
Highly Cited
2011
Highly Cited
2011
Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer
BackgroundThe research emphasis in anti-cancer drug discovery has always been to search for a drug with the greatest antitumor… 
Review
2011
Review
2011
Deletion of PTENP1 pseudogene in human melanoma
Dear Editor, The aberrant activation of the PI3K/AKT pathway in melanoma is known to be caused by genomic deletion, promoter… 
Highly Cited
2009
Highly Cited
2009
New primers for promising single-copy genes in fungal phylogenetics and systematics
Developing powerful phylogenetic markers is a key concern in fungal phylogenetics. Here we report degenerate primers that amplify… 
Highly Cited
2007
Highly Cited
2007
Human base excision repair complex is physically associated to DNA replication and cell cycle regulatory proteins
It has been hypothesized that a replication associated repair pathway operates on base damage and single strand breaks (SSB) at… 
Highly Cited
2006
Highly Cited
2006
Identification of biomarkers that distinguish human papillomavirus (HPV)-positive versus HPV-negative head and neck cancers in a mouse model
Head and neck squamous cell carcinoma (HNSCC) is a leading cause of cancer mortality worldwide. Recent reports have associated a… 
Highly Cited
2004
Highly Cited
2004
A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication
In vertebrates, MCM2–7 and Cdc45 are required for DNA replication initiation, but it is unknown whether they are also required… 
Highly Cited
2004
Highly Cited
2004
Gene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarrays.
Pancreatic ductal adenocarcinoma (PDAC) remains an important cause of malignancy-related death and is the eighth most common… 
Highly Cited
2003
Highly Cited
2003
The Cyclin D1-dependent Kinase Associates with the Pre-replication Complex and Modulates RB·MCM7 Binding*
The capacity of the cyclin D-dependent kinase to promote G1 progression through modulation of RB·E2F is well documented. We now… 
Highly Cited
1996
Highly Cited
1996
XMCM7, a novel member of the Xenopus MCM family, interacts with XMCM3 and colocalizes with it throughout replication.
A minichromosome maintenance (MCM) protein complex has been implicated in restricting DNA replication to once per cell cycle in… 
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