Skip to search formSkip to main contentSkip to account menu

MCC-555

Known as: MCC 555, RWJ-241947 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

netoglitazone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Peroxisome proliferator-activated receptor ligand MCC-555 suppresses intestinal polyps in ApcMin/+ mice via extracellular signal-regulated kinase and peroxisome proliferator-activated receptor…
A large body of studies has suggested that peroxisome proliferator-activated receptor γ (PPARγ) ligands, such as… 
2008
2008
Gene alterations by peroxisome proliferator-activated receptor gamma agonists in human colorectal cancer cells.
The peroxisome proliferator-activated receptor gamma (PPARgamma) is a nuclear transcription factor that controls the genes… 
2007
2007
Interaction of ligands for the peroxisome proliferator‐activated receptor γ with the endocannabinoid system
There is good evidence that agents interacting with the endocannabinoid system in the body can also interact with the peroxisome… 
Highly Cited
2006
Highly Cited
2006
A novel peroxisome proliferator–activated receptor γ ligand, MCC-555, induces apoptosis via posttranscriptional regulation of NAG-1 in colorectal cancer cells
Apoptosis and/or differentiation induction caused by the peroxisome proliferator–activated receptor γ (PPARγ) ligand is a… 
2005
2005
Thiazolidinediones inhibit proliferation of microvascular and macrovascular cells by a PPARγ-independent mechanism
Aims/hypothesisThis study evaluated the hypothesis that peroxisome proliferator-activated receptor-γ (PPARγ) agonists, including… 
2003
2003
Chronic treatment with the thiazolidinedione, MCC‐555, is associated with reductions in nitric oxide synthase activity and β‐cell apoptosis in the pancreas of the Zucker Diabetic Fatty rat
Summary.  The Zucker Diabetic Fatty (ZDF) rat is a model of impaired insulin sensitivity arising from hyperphagia owing to a… 
Review
2001
Review
2001
[KRP-297, MCC-555].
KRP-297 and MCC-555, which are being developed in Japan as thiazolidinediones, uniquely bind and activate peroxisome proliferator… 
Highly Cited
1998
Highly Cited
1998
A Potent Antidiabetic Thiazolidinedione with Unique Peroxisome Proliferator-activated Receptor γ-activating Properties*
Thiazolidinediones (TZDs) constitute an exciting new class of antidiabetic compounds, which function as activating ligands for… 
Highly Cited
1998
Highly Cited
1998
Improved metabolic status and insulin sensitivity in obese fatty (fa/fa) Zucker rats and Zucker Diabetic Fatty (ZDF) rats treated with the thiazolidinedione, MCC‐555
We examined the effect of chronic (21 days) oral treatment with the thiazolidinedione, MCC‐555 ((±)‐5‐[{6‐(2‐fluorbenzyl)‐oxy‐2… 
1998
1998
The new antidiabetic drug MCC-555 acutely sensitizes insulin signaling in isolated cardiomyocytes.
Freshly isolated adult rat ventricular cardiomyocytes have been used to characterize the action profile of the new… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)