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MBP gene

Known as: MYELIN A1 PROTEIN, BASIC, MYELIN MEMBRANE ENCEPHALITOGENIC PROTEIN, HMBP 
This gene plays a role in myelin sheath formation.
National Institutes of Health

Related topics

Related topics

3 relations
MBP protein, humanSRGN genenervous system development

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Cathepsin S and an asparagine‐specific endoprotease dominate the proteolytic processing of human myelin basic protein in vitro
The biochemical characterization of antigen degradation is an important basis for a better understanding of both the immune… 
Highly Cited
1998
Highly Cited
1998
Antibodies against IL-12 prevent superantigen-induced and spontaneous relapses of experimental autoimmune encephalomyelitis.
Immunization of (PL/J x SJL/J)F1 mice with myelin basic protein (MBP) induces relapsing experimental autoimmune encephalomyelitis… 
Highly Cited
1997
Highly Cited
1997
Triggers of autoimmune disease in a murine TCR-transgenic model for multiple sclerosis.
The combination of genetic and environmental factors that contribute to human autoimmune responses has made potential triggers of… 
Highly Cited
1996
Highly Cited
1996
Oral tolerance in myelin basic protein T-cell receptor transgenic mice: suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells.
Orally administered antigens induce a state of immunologic hyporesponsiveness termed oral tolerance. Different mechanisms are… 
Highly Cited
1994
Highly Cited
1994
Cloning and expression of myelin-associated oligodendrocytic basic protein. A novel basic protein constituting the central nervous system myelin.
Highly Cited
1994
Highly Cited
1994
Target organ-specific up-regulation of the MRC OX-40 marker and selective production of Th1 lymphokine mRNA by encephalitogenic T helper cells isolated from the spinal cord of rats with experimental…
Lewis x Buffalo F1 rat lymphocytes express both forms of the allelic marker RT7.1 (Lewis) and RT7.2 (Buffalo). We generated… 
Highly Cited
1988
Highly Cited
1988
Multiple discrete encephalitogenic epitopes of the autoantigen myelin basic protein include a determinant for I-E class II-restricted T cells
Immunization with the autoantigen myelin basic protein (MBP) causes experimental allergic encephalomyelitis (EAE). Initial… 
Review
1987
Review
1987
Immune reactivity in the nervous system: modulation of T-lymphocyte activation by glial cells.
The vertebrate central nervous system (CNS) has been traditionally thought to be inaccessible for the passenger lymphocytes of… 
Highly Cited
1987
Highly Cited
1987
Myelin basic protein and proteolipid protein reactivity of brain- and cerebrospinal fluid-derived T cell clones in multiple sclerosis and postinfectious encephalomyelitis.
T cells were directly cloned from autopsied MS brain plaque tissue and reactivity was measured with the major encephalitogenic… 
Highly Cited
1985
Highly Cited
1985
Substrate specificity of phospholipid/Ca2+-dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein.
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