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MBD4 wt Allele

Known as: MED1, Methyl-CpG Binding Domain Protein 4 wt Allele 
Human MBD4 wild-type allele is located in the vicinity of 3q21.3 and is approximately 9 kb in length. This allele, which encodes methyl-CpG-binding… 
National Institutes of Health

Related topics

Related topics

4 relations
DNA RepairHydrolysisMismatch Repairdna binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Nuclear receptor binding capacity of MED1 is required for maintaining body temperature at cold environment
2016
2016
The role of MED1 in breast carcinogenesis and progression
2010
2010
Abstract LB-57: Integral role of Med1 in conferring tamoxifen resistance to poor prognosis (luminal-B) estrogen receptor positive breast cancer
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC Background: Gene expression studies have… 
2010
2010
Dual Mode of Involvement of Transcriptional Mediator Subunit MED1 In GATA1-Mediated Erythroid Differentiation of K562 Erythroleukemia Cells
Abstract 3865 Mediator/TRAP complex, a master transcriptional coregulator, constitutes a subcomplex of RNA polymerase II… 
2010
2010
Peroxisome-proliferator-activated receptor-binding protein (PBP) is essential for the growth of active Notch4-immortalized mammary epithelial cells by activating SOX10 expression.
PBP (peroxisome-proliferator-activated receptor-binding protein) [Med1 (mediator 1)/TRAP220 (thyroid-hormone-receptor-associated… 
2010
2010
The Transcriptional Mediator Subunit MED1/TRAP220 in Stromal Cells Is Involved in Hematopoietic Stem/Progenitor Cell Support through Osteopontin Expression
ABSTRACT MED1/TRAP220, a subunit of the transcriptional Mediator/TRAP complex, is crucial for various biological events through… 
2009
2009
Peroxisome-proliferator-activated receptor-binding protein ( PBP ) is essential for the growth of active Notch 4-immortalized mammary epithelial cells by activating SOX 10 expression
Yiwei Tony ZHU*, Yuzhi JIA*, Liping HU*, Chao QI*, Megana K. PRASAD†, Andrew S. MCCALLION†‡ and Yi-Jun ZHU*1 *Department of… 
2003
2003
MED1: A central molecule for maintenance of genome integrity and response to DNA damage
Maintaining genome integrity is a dynamic process that involves many different cellular pathways, including methylation… 
Highly Cited
2000
Highly Cited
2000
Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domain.
The human DNA repair protein MED1 (also known as MBD4) was isolated as an interactor of the mismatch repair protein MLH1 in a… 
1985
1985
MED1: An intelligent computer program for thoracic pain diagnosis
SummaryMED1 is a fully implemented, medical expert system providing assistance in the diagnosis of patients complaining of chest… 
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