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Asymmetric total synthesis of clavolonine.
The asymmetric total synthesis of clavolonine (1) has been achieved based on chiral auxiliary multiple-use methodology. Our synthetic route features stereoselective transformations on the cyclohexaneExpand
The first asymmetric total syntheses of both enantiomers of cryptocaryone
The first asymmetric total syntheses of the (+)- and (−)-cryptocaryones are described. Removal of the acetal unit of the enone acetal 5, which was obtained in our previous study from theExpand
Asymmetric total synthesis of (-)-stenine and 9a-epi-stenine.
TLDR
The results of this effort demonstrate the applicability of the chiral auxiliary based strategy to the preparation of naturally occurring alkaloids that contain highly functionalized cyclohexane cores. Expand
Intramolecular iodoetherification of ene or diene ketals: facile synthesis of spiroketals.
A novel and rapid approach to chiral mono- or di-substituted spiroketals based on remote asymmetric induction by intramolecular iodoetherification of ene or diene ketals has been developed. ThisExpand
Intramolecular Iodoetherification of Ene or Diene Ketals: Facile Synthesis of Spiroketals.
Chiral spiroketals (II), (VI) and (IX) are synthesized based on remote asymmetric induction.