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MAPRE1 gene

Known as: MAPRE1, EB1, ADENOMATOUS POLYPOSIS COLI-BINDING PROTEIN EB1 
This gene is involved in the regulation of microtubule assemblies and chromosome stability.
National Institutes of Health

Related topics

Related topics

5 relations
Cell ProliferationCytoskeletal ModelingLigand BindingMAPRE1 protein, human

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MAPRE1 wt Allele

Papers overview

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Highly Cited
2013
Highly Cited
2013
Synergy between XMAP215 and EB1 increases microtubule growth rates to physiological levels
In cells, a complex network of proteins regulates the dynamic growth of microtubules that is essential for division and migration… 
Highly Cited
2006
Highly Cited
2006
Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1‐ or APC‐depleted cells
The correct formation of stable but dynamic links between chromosomes and spindle microtubules (MTs) is essential for accurate… 
Highly Cited
2006
Highly Cited
2006
Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1.
In interphase cells, the adenomatous polyposis coli (APC) protein accumulates on a small subset of microtubules (MTs) in cell… 
Highly Cited
2005
Highly Cited
2005
EB1 and EB3 control CLIP dissociation from the ends of growing microtubules.
EBs and CLIPs are evolutionarily conserved proteins, which associate with the tips of growing microtubules, and regulate… 
Highly Cited
2003
Highly Cited
2003
Metal tolerance and biosorption capacity of Bacillus circulans strain EB1.
Highly Cited
2003
Highly Cited
2003
The microtubule plus-end proteins EB1 and dynactin have differential effects on microtubule polymerization.
Several microtubule-binding proteins including EB1, dynactin, APC, and CLIP-170 localize to the plus-ends of growing microtubules… 
Highly Cited
2002
Highly Cited
2002
Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.
EB1 is a microtubule tip-associated protein that interacts with the APC tumor suppressor protein and components of the dynein… 
Highly Cited
2002
Highly Cited
2002
EB1 targets to kinetochores with attached, polymerizing microtubules.
Microtubule polymerization dynamics at kinetochores is coupled to chromosome movements, but its regulation there is poorly… 
Highly Cited
2000
Highly Cited
2000
Regulation and function of the interaction between the APC tumour suppressor protein and EB1
The interaction between the adenomatous polyposis coli (APC) tumour suppressor and the microtubule-associated protein EB1 was… 
Highly Cited
1989
Highly Cited
1989
The Epstein‐Barr virus early protein EB1 activates transcription from different responsive elements including AP‐1 binding sites.
When expressed in Epstein‐Barr virus (EBV) latently infected B cells, the EBV early protein EB1 trans‐activates as many EBV early… 
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