MAPK8 gene

Known as: STRESS-ACTIVATED PROTEIN KINASE JNK1, JNK, SAPK1 
This gene plays a role in signal transduction that affects cell differentiation, growth and proliferation. It is also involved in mediation of both… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2018
0102019942018

Papers overview

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Highly Cited
2008
Highly Cited
2008
JNK proteins have been shown to be involved in liver carcinogenesis in mice, but the extent of their involvement in the… (More)
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Highly Cited
2007
Highly Cited
2007
Obesity-induced insulin resistance is a major factor in the etiology of type 2 diabetes, and Jun kinases (JNKs) are key negative… (More)
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Highly Cited
2006
Highly Cited
2006
A major link between inflammation and cancer is provided by NF-kappaB transcription factors. Ikkbeta(Deltahep) mice, which… (More)
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Highly Cited
2003
Highly Cited
2003
Microtubules (MTs) play an important role in elaboration and maintenance of axonal and dendritic processes. MT dynamics are… (More)
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Highly Cited
2002
Highly Cited
2002
Efficient wound healing including clotting and subsequent reepithelization is essential for animals ranging from insects to… (More)
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Highly Cited
2001
Highly Cited
2001
Apoptotic and mitogenic stimuli activate c-Jun NH2-terminal kinases (JNKs) in T cells. Although T cells express both JNK1 and… (More)
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Highly Cited
1997
Highly Cited
1997
Inhibition of protein synthesis per se does not potentiate the stress-activated protein kinases (SAPKs; also known as cJun NH2… (More)
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Highly Cited
1997
Highly Cited
1997
E-selectin expression by endothelium is crucial for leukocyte recruitment during inflammatory responses. Transcriptional… (More)
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Highly Cited
1994
Highly Cited
1994
The ultraviolet (UV) response of mammalian cells is characterized by a rapid and selective increase in gene expression mediated… (More)
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Highly Cited
1994
Highly Cited
1994
The transcriptional activity of c-Jun is augmented through phosphorylation at two sites by a c-Jun amino-terminal kinase (JNK… (More)
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