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MAP2K3 gene

Known as: MEK3, Mitogen-Activated Protein Kinase Kinase 3 Gene, MKK3 
This gene is involved in stress-mediated signaling.
National Institutes of Health

Related topics

Related topics

8 relations
Cytokine SignalingImmune responseMAP Kinase Kinase 3MAP2K3 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Molecular Changes Involving MEK3–p38 MAPK Activation in Chronic Masticatory Myalgia
The exact mechanism underlying chronic masticatory myalgia (CMM), a conspicuous symptom in temporomandibular disorders, remains… 
2015
2015
MKK3 mediates inflammatory response through modulation of mitochondrial function.
2015
2015
Effect of combination therapy of propofol and sevoflurane on MAP2K3 level and myocardial apoptosis induced by ischemia-reperfusion in rats.
To investigate the mechanism of combination therapy of propofol and sevoflurane on MAP2K3 level and myocardial apoptosis induced… 
Highly Cited
2012
Highly Cited
2012
miR-20a represses endothelial cell migration by targeting MKK3 and inhibiting p38 MAP kinase activation in response to VEGF
Endothelial cell migration induced in response to vascular endothelial growth factor (VEGF) is a crucial step of angiogenesis and… 
2010
2010
Proteome profiling of immortalization‐to‐senescence transition of human breast epithelial cells identified MAP2K3 as a senescence‐promoting protein which is downregulated in human breast cancer
Purpose: Immortalization is one of the first changes in cells undergoing carcinogenic transformation. Proteome profiling of the… 
2006
2006
Role of MKK3 and p38 MAPK in cytokine-induced death of insulin-producing cells.
The aim of the present investigation was to elucidate further the importance of p38 MAPK (mitogen-activated protein kinase) in… 
2005
2005
The Survival Kinase Mirk/dyrk1B Is Activated through Rac1-MKK3 Signaling*
The serine/threonine kinase Mirk/dyrk1B is activated in several solid tumors where it mediates cell survival, but the mechanism… 
2001
2001
Parallel Regulation of Mitogen-activated Protein Kinase Kinase 3 (MKK3) and MKK6 in Gq-signaling Cascade*
Heterotrimeric G protein Gq stimulates the activity of p38 mitogen-activated protein kinase (MAPK) in mammalian cells. To… 
1999
1999
Both p 38 a MAPK and JNK / SAPK Pathways Are Important for Induction of Nitric-oxide Synthase by Interleukin-1 b in Rat Glomerular Mesangial Cells
Interleukin 1b (IL-1b) induces expression of the inducible nitric-oxide synthase (iNOS) with concomitant release of nitric oxide… 
1999
1999
Both p38alpha(MAPK) and JNK/SAPK pathways are important for induction of nitric-oxide synthase by interleukin-1beta in rat glomerular mesangial cells.
Interleukin 1beta (IL-1beta) induces expression of the inducible nitric-oxide synthase (iNOS) with concomitant release of nitric… 
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