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MAP Kinase Cascade

Known as: MAPK cascade, MAPKKK cascade, MAP Kinase Module 
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the… 
National Institutes of Health

Related topics

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Narrower (8)

MAP kinase activityMAP kinase kinase activityMAP kinase kinase kinase activityMAP kinase kinase kinase kinase activity
MAPK signalingnegative regulation of MAPK cascade

Papers overview

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Highly Cited
2003
Highly Cited
2003
Nicotiana benthamiana gp91phox Homologs NbrbohA and NbrbohB Participate in H2O2 Accumulation and Resistance to Phytophthora infestans Article, publication date, and citation information can be found…
Active oxygen species (AOS) are responsible for triggering defense responses in plants. Respiratory burst oxidase homologs (rboh… 
Review
2003
Review
2003
Nectins and nectin‐like molecules: Roles in cell adhesion, migration, and polarization
Nectins are a family of Ca2+‐independent immunoglobulin‐like cell‐cell adhesion molecules consisting of four members, which… 
Highly Cited
2003
Highly Cited
2003
Modulation of Pro-survival Akt/Protein Kinase B and ERK1/2 Signaling Cascades by Quercetin and Its in Vivo Metabolites Underlie Their Action on Neuronal Viability*
Much recent interest has focused on the potential of flavonoids to interact with intracellular signaling pathways such as with… 
Highly Cited
2003
Highly Cited
2003
Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation
The extracellular signal-regulated kinase (ERK) is a component of the mitogen-activated protein kinase cascade. Exon 2 of erk2… 
Highly Cited
2003
Highly Cited
2003
SHP2 and SOCS3 Contribute to Tyr-759-dependent Attenuation of Interleukin-6 Signaling through gp130*
Interleukin-6 (IL-6) activates the Jak/STAT pathway as well as the mitogen-activated protein kinase cascade. Tyrosine 759 of the… 
Highly Cited
1999
Highly Cited
1999
Suppression of Ras-Induced Apoptosis by the Rac GTPase
ABSTRACT Ras is an essential component of signal transduction pathways that control cell proliferation, differentiation, and… 
Highly Cited
1998
Highly Cited
1998
Fluid shear stress activation of egr-1 transcription in cultured human endothelial and epithelial cells is mediated via the extracellular signal-related kinase 1/2 mitogen-activated protein kinase…
The primary response transcription factor, early growth response-1 (Egr-1), is rapidly activated by a variety of extracellular… 
Highly Cited
1998
Highly Cited
1998
SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis.
SEK1 (MKK4/JNKK) is a mitogen-activated protein kinase activator that has been shown to participate in vitro in two stress… 
Highly Cited
1996
Highly Cited
1996
Rho1p, a Yeast Protein at the Interface Between Cell Polarization and Morphogenesis
The enzyme that catalyzes the synthesis of the major structural component of the yeast cell wall, β(1→3)-D-glucan synthase (also… 
Highly Cited
1993
Highly Cited
1993
Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6.
NF-IL6, a member of the basic leucine zipper (bZIP) family transcription factors, is involved in expression of inducible genes… 
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