Skip to search formSkip to main contentSkip to account menu

MAD2L1 gene

Known as: MITOTIC ARREST-DEFICIENT 2, S. CEREVISIAE, HOMOLOG-LIKE 1, MAD2 mitotic arrest deficient-like 1 (yeast), MAD2, S. CEREVISIAE, HOMOLOG OF 
This gene is involved in mitosis.
National Institutes of Health

Related topics

Related topics

5 relations
Cell Cycle ControlMitotic Spindle Assembly Checkpoint Protein MAD2AMitotic Spindle CheckpointsPrometaphase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Chk1 is required for the metaphase-anaphase transition via regulating the expression and localization of Cdc20 and Mad2.
2013
2013
Chk1-Mad2 interaction
Chk1 is implicated in several checkpoints of the cell cycle acting as a key player in the signal transduction pathway activated… 
2011
2011
CHFR binds to and regulates MAD2 in the spindle checkpoint through its cysteine-rich domain.
2011
2011
Knockdown of Mad2 induces osteosarcoma cell apoptosis-involved Rad21 cleavage
BackgroundBesides Mad2’s role in carcinogenesis, recent study has shown that it is essential in cell survival. Here we found that… 
2010
2010
Sustained Mps 1 activity is required in mitosis to recruit O-Mad 2 to the Mad 1 – C-Mad 2 core complex
The Mps1 protein kinase plays an essential role in the spindle assembly checkpoint (SAC; Weiss and Winey, 1996), an inhibitory… 
Highly Cited
2009
Highly Cited
2009
Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs
The DNA-dependent adenosine triphosphatase (ATPase) Plk1-interacting checkpoint helicase (PICH) has recently been implicated in… 
2009
2009
Expression of mitotic checkpoint proteins BUB1B and MAD2L1 in salivary duct carcinomas.
OBJECTIVE Defects in the mitotic checkpoint lead to aneuploidy and might facilitate tumorigenesis. However, the ploidy status in… 
2008
2008
MAD2 interacts with DNA repair proteins and negatively regulates DNA damage repair.
2003
2003
p55CDC/hCDC20 mutant induces mitotic catastrophe by inhibiting the MAD2-dependent spindle checkpoint activity in tumor cells.
2001
2001
Dioxin suppresses the checkpoint protein, MAD2, by an aryl hydrocarbon receptor-independent pathway.
The compound 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has been shown recently to be carcinogenic, but little is currently known… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)