MAD2L1 gene

Known as: MITOTIC ARREST-DEFICIENT 2, S. CEREVISIAE, HOMOLOG-LIKE 1, MAD2 mitotic arrest deficient-like 1 (yeast), MAD2, S. CEREVISIAE, HOMOLOG OF 
This gene is involved in mitosis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
05101519902018

Papers overview

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Highly Cited
2009
Highly Cited
2009
Premature anaphase onset is prevented by the mitotic checkpoint through production of a "wait anaphase" inhibitor(s) that blocks… (More)
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2009
2009
Genomic instability is a hallmark of human cancers. Spindle assembly checkpoint (SAC) is a critical cellular mechanism that… (More)
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Highly Cited
2008
Highly Cited
2008
The spindle assembly checkpoint (SAC) is required to block sister chromatid separation until all chromosomes are properly… (More)
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Highly Cited
2005
Highly Cited
2005
In mitosis, the spindle checkpoint protein Mad2 averts aneuploidy by delaying anaphase onset until chromosomes align. Here we… (More)
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Highly Cited
2004
Highly Cited
2004
The spindle checkpoint ensures accurate chromosome segregation by delaying anaphase in response to misaligned sister chromatids… (More)
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Highly Cited
2002
Highly Cited
2002
The spindle assembly checkpoint monitors the attachment of kinetochores to the mitotic spindle and the tension exerted on… (More)
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Highly Cited
2002
Highly Cited
2002
The spindle checkpoint protein Mad1 recruits Mad2 to unattached kinetochores and is essential for Mad2-Cdc20 complex formation in… (More)
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Highly Cited
2001
Highly Cited
2001
Mad2 is a key component of the spindle checkpoint, a device that controls the fidelity of chromosome segregation in mitosis. The… (More)
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2000
2000
Breast cancer is a heterogeneous disorder in which most tumors display some degree of aneuploidy, especially those at later… (More)
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Highly Cited
1998
Highly Cited
1998
We have investigated the function of p55CDC, a mammalian protein related to Cdc20 and Hct1/Cdh1 in Saccharomyces cerevisiae, and… (More)
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