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M-ficolin

Known as: ficolin A, ficolin-A, ficolin-alpha 
National Institutes of Health

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Broader (1)

ficolin

Papers overview

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2020
2020
Ficolin A derived from local macrophages and neutrophils protects against LPS-induced acute lung injury by activating complement.
Ficolins are important and widely distributed pattern recognition molecules that can induce lectin complement pathway activation… 
Review
2013
Review
2013
Ficolins in complement activation.
Highly Cited
2012
Highly Cited
2012
Mice Deficient in Ficolin, a Lectin Complement Pathway Recognition Molecule, Are Susceptible to Streptococcus pneumoniae Infection
Mannose-binding lectin (MBL) and ficolin are complexed with MBL-associated serine proteases, key enzymes of complement activation… 
Highly Cited
2012
Highly Cited
2012
L-Ficolin Binds to the Glycoproteins Hemagglutinin and Neuraminidase and Inhibits Influenza A Virus Infection Both in vitro and in vivo
L-ficolin, one of the complement lectins found in human serum, is a novel pattern recognition molecule that can specifically bind… 
2012
2012
M‐ficolin and leukosialin (CD43): new partners in neutrophil adhesion
M‐ficolin specificity for sialylated ligands prompted us to investigate its interactions with the main membrane sialoprotein of… 
2012
2012
Mouse Ficolin B Has an Ability to Form Complexes with Mannose-Binding Lectin-Associated Serine Proteases and Activate Complement through the Lectin Pathway
Ficolins are thought to be pathogen-associated-molecular-pattern-(PAMP-) recognition molecules that function to support innate… 
Highly Cited
2009
Highly Cited
2009
Local Inflammation Induces Complement Crosstalk Which Amplifies the Antimicrobial Response
By eliciting inflammatory responses, the human immunosurveillance system notably combats invading pathogens, during which acute… 
Highly Cited
2009
Highly Cited
2009
Interactions of Ficolin and Mannose-Binding Lectin with Fibrinogen/Fibrin Augment the Lectin Complement Pathway
Ficolin and mannose-binding lectin (MBL) are animal lectins that are involved in innate immunity by initiating the lectin… 
2007
2007
Identification of a functionally relevant signal peptide of mouse ficolin A.
Mouse ficolin A is a plasma protein with lectin activity, and plays a role in host defense by binding carbohydrates, especially… 
Highly Cited
2005
Highly Cited
2005
Carbohydrate-binding specificities of mouse ficolin A, a splicing variant of ficolin A and ficolin B and their complex formation with MASP-2 and sMAP
Ficolins are a group of proteins mainly consisting of collagen-like and fibrinogen-like domains and are thought to play a role in… 
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