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Multilocus Sequence Typing System for Group B Streptococcus
TLDR
The GBS MLST system offers investigators a valuable typing tool that will promote further investigation of the population biology of this organism and suggests that recombination occurs at the capsular locus. Expand
Phylogenetic relationships among Streptococcus agalactiae isolated from piscine, dolphin, bovine and human sources: a dolphin and piscine lineage associated with a fish epidemic in Kuwait is also
TLDR
Comparative genomics of piscine, human and bovine GBS could help clarify those genes important for host tropism, the emergence of unique pathogenic clones and whether these hosts act as reservoirs of one another's pathogenic lineages. Expand
Phylogenetic Lineages of Invasive and Colonizing Strains of Serotype III Group B Streptococci from Neonates: a Multicenter Prospective Study
TLDR
The hypothesis that ST-17 complex GBS are more virulent than other serotype III GBS is supported, and lineages associated with invasive disease are determined. Expand
The evolutionarily conserved G protein-coupled receptor SREB2/GPR85 influences brain size, behavior, and vulnerability to schizophrenia
TLDR
It is shown that SREB2 is involved in determining brain size, modulating diverse behaviors, and potentially in vulnerability to schizophrenia, and its pathway as a target for psychiatric therapy. Expand
Limited Genetic Diversity of Recent Invasive Isolates of Non-Serotype b Encapsulated Haemophilus influenzae
TLDR
The genetic relationships of 48 recently isolated invasive H. influenzae type a, e, and f strains are characterized by comparison of restriction digest patterns (RDPs), consistent with the hypothesis that the increased incidence of disease due to non-type b encapsulated H. Influenzae reflects the emergence of hypervirulent clones. Expand
Role of L-Ficolin/Mannose-Binding Lectin-Associated Serine Protease Complexes in the Opsonophagocytosis of Type III Group B Streptococci1
TLDR
It is concluded that binding of L-ficolin/mannose-binding lectin-associated serine protease (MASP) complexes in Ca2+-dependent, Ab-independent opsonophagocytosis of serotype III GBS generates C3 convertase C4b2a, which deposits C3b on GBS. Expand
Next-generation sequencing reveals genomic features in the Japanese quail.
TLDR
The draft genome of the Japanese quail was sequenced and assembled using next-generation sequencing technology and 100 microsatellite markers were developed and used to evaluate the genetic variability and diversity of 11 lines of Japanese quails. Expand
Subtractive Hybridization Identifies a Novel Predicted Protein Mediating Epithelial Cell Invasion by Virulent Serotype III Group B Streptococcus agalactiae
TLDR
Observations suggest that Spb1 contributes to the pathogenesis of neonatal GBS infection by mediating internalization of virulent serotype III GBS and confirm that understanding of the population structure of bacteria may lead to insights into the pathogenic of human infections. Expand
Expression of nerve growth factor (NGF), and its receptors trkA and p75 in ovaries of the cyclic golden hamster (Mesocricetus auratus) and the regulation of their production by luteinizing hormone.
TLDR
The distinct widespread distribution of NGF and its two receptors in the ovary of golden hamsters suggest that NGF may be an important growth factor for regulation of ovarian function and the LH surge may be a important factor for inducing production of N GF and itsTwo receptors in interstitial cells of the cyclic golden hamster. Expand
Correlation of phylogenetic lineages of group B Streptococci, identified by analysis of restriction-digestion patterns of genomic DNA, with infB alleles and mobile genetic elements.
TLDR
The purpose of the present study was to correlate GBS RDP types and alleles of the highly conserved gene encoding translation-initiation factor IF2, infB, and/or the inserted elements IS1548 and GBSi1. Expand
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