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Lysine Carboxypeptidase

Known as: Inactivator, Anaphylatoxin, Anaphylatoxin Inactivator, Lysine Carboxypeptidase [Chemical/Ingredient] 
A metallocarboxypeptidase that removes C-terminal basic amino acid from peptides and proteins, with preference shown for lysine over arginine. It is… 
National Institutes of Health

Related topics

Related topics

9 relations
CPN1 geneCarboxypeptidase B2In BloodProcess of secretion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Proteolytic cleavage of carboxypeptidase N markedly increases its antifibrinolytic activity
Summary.  Background: Carboxypeptidase N (CPN) is a constitutively active basic carboxypeptidase sharing specificity with… 
2002
2002
Elastase from Activated Human Neutrophils Activates Procarboxypeptidase R
Carboxypeptidase R (EC 3.4.17.20; CPR) is an unstable basic carboxypeptidase found in fresh serum in addition to carboxypeptidase… 
Highly Cited
2001
Highly Cited
2001
Pathways of bradykinin degradation in blood and plasma of normotensive and hypertensive rats.
Kinins are vasoactive peptide hormones that can confer protection against the development of hypertension. Because their efficacy… 
1999
1999
Arginine Carboxypeptidase (CPR) in Human Plasma Determined with Sandwich ELISA
There are two types of carboxypeptidases present in human blood, carboxypeptidase N (CPN) and arginine carboxypeptidase (CPR… 
1992
1992
Endopeptidase and carboxypeptidase activities in human urine which hydrolyze bradykinin.
1. We have fractionated the bradykinin inactivating activity of human urine by stepwise elution chromatography on DEAE-cellulose… 
1991
1991
Metabolism of bradykinin analogs by angiotensin I converting enzyme and carboxypeptidase N
1980
1980
Chemotactic activity of C5ades Arg: evidence of a requirement for an anionic peptide 'helper factor' and inhibition by a cationic protein in serum from patients with systemic lupus erythematosus.
Highly Cited
1977
Highly Cited
1977
Blood vessel-hormone interactions: angiotensin, bradykinin, and prostaglandins.
Isolated Krebs-perfused rabbit-mesentery blood vessels release a prostaglandin E-like substance (PGE) when treated with… 
Highly Cited
1973
Highly Cited
1973
Changes in bradykinin level in coronary sinus blood after the experimental occlusion of a coronary artery.
1971
1971
Peptide inhibitors of pulmonary angiotensin I converting enzyme.
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