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Lymphocytes, Tumor-Infiltrating

Known as: Tumor Infiltrating Lymphocyte, Tumor-Infiltrating Lymphocyte, Tumor-Infiltrating Lymphocytes 
Lymphocytes that show specificity for autologous tumor cells. Ex vivo isolation and culturing of TIL with interleukin-2, followed by reinfusion into… 
National Institutes of Health

Related topics

Related topics

14 relations
Adoptive ImmunotherapyHematopoietic and Lymphoid TissueLymphoid TissueMAGE-12: 170-178 Peptide

Broader (2)

Cytotoxic T-LymphocytesLymphocyte

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Tumor-Infiltrating Lymphocytes Expressing the Tissue Resident Memory Marker CD103 Are Associated with Increased Survival in High-Grade Serous Ovarian Cancer
Background: The presence of CD8+ tumor-infiltrating lymphocytes (TIL) is associated with prolonged survival in high-grade serous… 
Highly Cited
2013
Highly Cited
2013
Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors.
Tumor progression is facilitated by regulatory T cells (Treg) and restricted by effector T cells. In this study, we document… 
Highly Cited
2013
Highly Cited
2013
Adoptive Transfer of Tumor-Infiltrating Lymphocytes in Patients with Metastatic Melanoma: Intent-to-Treat Analysis and Efficacy after Failure to Prior Immunotherapies
Purpose: Adoptive cell transfer (ACT) using autologous tumor-infiltrating lymphocytes (TIL) was reported to yield objective… 
Highly Cited
2013
Highly Cited
2013
Immune infiltrates are prognostic factors in localized gastrointestinal stromal tumors.
Cancer immunosurveillance relies on effector/memory tumor-infiltrating CD8(+) T cells with a T-helper cell 1 (TH1) profile… 
Highly Cited
2010
Highly Cited
2010
Tumor‐infiltrating IL‐17‐producing γδ T cells support the progression of tumor by promoting angiogenesis
Based on the evidence that IL‐17 is a key cytokine involved in various inflammatory diseases, we explored the critical role of IL… 
Highly Cited
2008
Highly Cited
2008
Inverse Correlation between Tumoral Indoleamine 2,3-Dioxygenase Expression and Tumor-Infiltrating Lymphocytes in Endometrial Cancer: Its Association with Disease Progression and Survival
Purpose: Tumor escape from host immune systems is a crucial mechanism for disease progression. We recently showed that the… 
Highly Cited
2007
Highly Cited
2007
High-level expression of chemokine CXCL16 by tumor cells correlates with a good prognosis and increased tumor-infiltrating lymphocytes in colorectal cancer.
CXCL16 is a new member of the chemokine superfamily, which exists in a transmembrane as well as a soluble form. Its receptor… 
Highly Cited
2006
Highly Cited
2006
Expression of LAG-3 by tumor-infiltrating lymphocytes is coincident with the suppression of latent membrane antigen-specific CD8+ T-cell function in Hodgkin lymphoma patients.
In Hodgkin lymphoma (HL), the malignant Hodgkin Reed-Sternberg (HRS) cells constitute only 0.5% of 10% of the diseased tissue… 
Highly Cited
2004
Highly Cited
2004
Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy.
Highly Cited
1994
Highly Cited
1994
Oligoclonality of tumor-infiltrating lymphocytes from human melanomas.
A PCR-based method that determines VDJ junction size patterns in 24 human TCR V beta subfamilies was used to analyze T cells… 
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