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Luciferases, Firefly

Known as: Photinus luciferin 4 monooxygenase, Firefly Luciferases, firefly luciferase 
Luciferases from FIREFLIES, usually Photinus, that oxidizes FIREFLY LUCIFERIN to cause emission of PHOTONS.
National Institutes of Health

Related topics

Related topics

10 relations
In BloodPhotinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activityProcess of secretionantagonists & inhibitors

Broader (1)

Luminescent Agents

Narrower (1)

WIN3 protein, Arabidopsis

Papers overview

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Highly Cited
2010
Highly Cited
2010
Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124
Firefly luciferase (FLuc), an ATP-dependent bioluminescent reporter enzyme, is broadly used in chemical biology and drug… 
Highly Cited
2010
Highly Cited
2010
Robust light emission from cyclic alkylaminoluciferin substrates for firefly luciferase.
Firefly luciferase utilizes the chemical energy of ATP and oxygen to convert its substrate, D-luciferin, into an excited-state… 
Review
2005
Review
2005
Spying on cancer: molecular imaging in vivo with genetically encoded reporters.
Highly Cited
2004
Highly Cited
2004
Kinetic analysis and modeling of firefly luciferase as a quantitative reporter gene in live mammalian cells
Firefly luciferase has proven to be a highly sensitive and quantitative reporter gene for studying gene delivery and regulation… 
Highly Cited
2002
Highly Cited
2002
In the complex family of heat stress transcription factors, HsfA1 has a unique role as master regulator of thermotolerance in tomato.
We generated transgenic tomato plants with altered expression of heat stress transcription factor HsfA1. Plants with 10-fold… 
Highly Cited
2001
Highly Cited
2001
Split luciferase as an optical probe for detecting protein-protein interactions in mammalian cells based on protein splicing.
We describe a new method for detecting protein-protein interactions in intact mammalian cells; the approach is based on protein… 
Highly Cited
1999
Highly Cited
1999
Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase.
We have developed a method for measuring the local concentration of ATP at the extracellular surface of live cells. This method… 
Highly Cited
1998
Highly Cited
1998
Luminescent bacterial sensor for cadmium and lead.
Highly Cited
1996
Highly Cited
1996
Dual-Luciferase TM Reporter Assay: An Advanced Co-Reporter Technology Integrating Firefly and Renilla Luciferase Assays
In the quantitation of gene expression using firefly luciferase, a second reporter gene is commonly used to minimize experimental… 
Highly Cited
1991
Highly Cited
1991
Modulation of firefly luciferase stability and impact on studies of gene regulation.
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