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Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity

Known as: firefly luciferase activity, Photinus luciferin 4-monooxygenase (adenosine triphosphate-hydrolyzing), Photinus-luciferin:oxygen 4-oxidoreductase (decarboxylating, ATP-hydrolysing) 
Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin. [EC:1.13.12.7, MetaCyc:1.13… 
National Institutes of Health

Related topics

Related topics

2 relations
Luciferases, Firefly

Broader (1)

luciferin monooxygenase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Molecular enigma of multicolor bioluminescence of firefly luciferase
Firefly luciferase-catalyzed reaction proceeds via the initial formation of an enzyme-bound luciferyl adenylate intermediate. The… 
Review
2009
Review
2009
Functional assessment of isolated mitochondria in vitro.
Highly Cited
2008
Highly Cited
2008
Uptake kinetics and biodistribution of 14C-d-luciferin—a radiolabeled substrate for the firefly luciferase catalyzed bioluminescence reaction: impact on bioluminescence based reporter gene imaging
PurposeFirefly luciferase catalyzes the oxidative decarboxylation of d-luciferin to oxyluciferin in the presence of cofactors… 
Highly Cited
2006
Highly Cited
2006
Design of expression vectors for RNA interference based on miRNAs and RNA splicing
RNA interference (RNAi) mediates sequence‐specific post‐transcriptional gene silencing in many eukaryotes and is used for reverse… 
Highly Cited
2000
Highly Cited
2000
Analysis of genetic polymorphisms in the transforming growth factor-β1 gene and the risk of Alzheimer's disease
Abstract. Alzheimer's disease (AD) is a complex disease involving several genetic and environmental components. Genetic studies… 
Highly Cited
1995
Highly Cited
1995
Estradiol regulation of the human retinoic acid receptor alpha gene in human breast carcinoma cells is mediated via an imperfect half-palindromic estrogen response element and Sp1 motifs.
Estrogen receptor (ER)-positive human breast carcinoma (HBC) cell lines express significantly higher levels of retinoic acid… 
Highly Cited
1988
Highly Cited
1988
Expression of the firefly luciferase gene in vaccinia virus: a highly sensitive gene marker to follow virus dissemination in tissues of infected animals.
We have introduced the firefly luciferase gene of Photinus pyralis into the vaccinia virus genome. This gene is expressed in a… 
Highly Cited
1969
Highly Cited
1969
MECHANISM OF BIOLUMINESCENCE, CHEMI‐LUMINESCENCE AND ENZYME FUNCTION IN THE OXIDATION OF FIREFLY LUCIFERIN*,†
Abstract— The chemical steps and the products of the bioluminescent and chemiluminescent oxidations of firefly luciferin are… 
Highly Cited
1966
Highly Cited
1966
Studies on the flash communication system in Photinus fireflies
Review
1952
Review
1952
Firefly luminescence in the study of energy transfer mechanisms. I. Substrate and enzyme determination.
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