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Loss of Chromosome 7q

Known as: del(7q) 
A cytogenetic abnormality that refers to deletion of part of the long arm of chromosome 7. It is associated with the development of chronic… Expand
National Institutes of Health

Related topics

Related topics

11 relations
Chromosomes, Human, Pair 7Chronic Myelomonocytic Leukemia with EosinophiliaChronic Myelomonocytic Leukemia-1Chronic Myelomonocytic Leukemia-2
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Papers overview

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Highly Cited
2013
Highly Cited
2013
CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
Loss of chromosome 7 and del(7q) [-7/del(7q)] are recurring cytogenetic abnormalities in hematologic malignancies, including… Expand
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2012
2012
Expression profiling of uterine leiomyomata cytogenetic subgroups reveals distinct signatures in matched myometrium: transcriptional profilingof the t(12;14) and evidence in support of predisposing…
Uterine leiomyomata (UL), the most common neoplasm in reproductive-age women, are classified into distinct genetic subgroups… Expand
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Highly Cited
2007
Highly Cited
2007
Monosomy 7 and deletion 7q in children and adolescents with acute myeloid leukemia: an international retrospective study.
Monosomy 7 (-7) and deletion 7q \del(7q)] are rare in childhood acute myeloid leukemia (AML). We retrospectively collected data… Expand
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Highly Cited
2002
Highly Cited
2002
Balanced chromosome abnormalities inv(16) and t(15;17) in therapy-related myelodysplastic syndromes and acute leukemia: report from an international workshop.
The Workshop identified 48 unselected patients with therapy-related myelodysplastic syndrome or acute myeloid leukemia (t-MDS/t… Expand
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2002
2002
Unique balanced chromosome abnormalities in treatment-related myelodysplastic syndromes and acute myeloid leukemia: report from an international workshop.
A total of 123 balanced rearrangements, including 26 occurring as a sole anomaly, not known to be recurrent in myelodysplastic… Expand
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2001
2001
Splenic marginal zone B-cell lymphomas: two cytogenetic subtypes, one with gain of 3q and the other with loss of 7q.
BACKGROUND AND OBJECTIVES Splenic marginal zone B-cell lymphoma (SMZBCL) has clinical, immunophenotypic and histologic features… Expand
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1999
1999
Delineation of multiple deleted regions in 7q in myeloid disorders.
Loss of chromosome material due to deletions of the long arm of chromosome 7, del(7q), is a consistent finding in all types of… Expand
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1999
1999
Characterization of the human myeloid leukemia-derived cell line GF-D8 by multiplex fluorescence in situ hybridization, subtelomeric probes, and comparative genomic hybridization.
The human myeloid leukemia cell line GF-D8 was established from the peripheral blood blasts of a patient with acute myeloid… Expand
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1992
1992
Cytogenetic studies of eight squamous cell carcinomas of the head and neck. Deletion of 7q, a possible primary chromosomal event.
Cytogenetic analysis was performed on the metaphase spreads obtained from primary cultures of eight squamous cell carcinomas… Expand
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1990
1990
Characteristic chromosome abnormalities, including rearrangements of 6p, del(7q), +12, and t(12;14), in 44 uterine leiomyomas
SummaryThe cytogenetic analysis of 224 leiomyomas from 138 patients is presented. An insufficient number of mitoses was found in… Expand
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