Long Interspersed Nucleotide Element-1

Known as: L1 Element, Elements, LINE-1, L1 
A long interspersed element (LINE) found in mammals. The LINE-1 element is the only active LINE in humans and is approximately 6,000 base pairs long… (More)
National Institutes of Health

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2 relations
Chromosomes

Broader (1)

Long Interspersed Elements

Papers overview

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2013
2013
Long interspersed nucleotide element 1 hypomethylation is associated with poor prognosis of lung adenocarcinoma.
BACKGROUND Genome-wide DNA hypomethylation is known to play important roles in genomic instability and carcinogenesis… (More)
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Review
2013
Review
2013
Long Interspersed Element–1 (LINE-1): Passenger or Driver in Human Neoplasms?
LINE-1 (L1) retrotransposons make up a significant portion of human genomes, with an estimated 500,000 copies per genome. Like… (More)
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2012
2012
Retrotransposon long interspersed nucleotide element-1 (LINE-1) is activated during salamander limb regeneration.
Salamanders possess an extraordinary capacity for tissue and organ regeneration when compared to mammals. In our effort to… (More)
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2011
2011
Methylation levels of the "long interspersed nucleotide element-1" repetitive sequences predict survival of melanoma patients
The prognosis of cutaneous melanoma (CM) differs for patients with identical clinico-pathological stage, and no molecular markers… (More)
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Highly Cited
2010
Highly Cited
2010
Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects.
BACKGROUND Impaired one-carbon metabolism is thought to be associated with the risk of neural tube defects (NTDs); however, the… (More)
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2010
2010
Induction of long interspersed nucleotide element-1 (L1) retrotransposition by 6-formylindolo[3,2-b]carbazole (FICZ), a tryptophan photoproduct.
Long interspersed nucleotide element-1 (L1) is a retroelement comprising about 17% of the human genome, of which 80-100 copies… (More)
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Highly Cited
2010
Highly Cited
2010
LINE-1 Retrotransposition Activity in Human Genomes
Highly active (i.e., "hot") long interspersed element-1 (LINE-1 or L1) sequences comprise the bulk of retrotransposition activity… (More)
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Highly Cited
2006
Highly Cited
2006
Cellular inhibitors of long interspersed element 1 and Alu retrotransposition.
Long interspersed element (LINE) 1 retrotransposons are major genomic parasites that represent approximately 17% of the human… (More)
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Highly Cited
2006
Highly Cited
2006
APOBEC3 proteins inhibit human LINE-1 retrotransposition.
The human cytidine deaminase family APOBEC3 represents a novel group of proteins in the field of innate defense mechanisms that… (More)
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Highly Cited
2005
Highly Cited
2005
Analysis of repetitive element DNA methylation by MethyLight
Repetitive elements represent a large portion of the human genome and contain much of the CpG methylation found in normal human… (More)
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